Phase 3 N=470 An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
Primary: Number of Adverse Events — 450; 362; 126; 206 events
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=16 Pilot Study to Assess the Effects of Hepatic Ultrasound Insonification on Subjects With T2DM
Type 2 Diabetes
Primary: Change From Baseline in Glucose Disposal Rate: Insulin Ratio During Steady State (M/I) — 0.055; 0.004 mg/kg/min per microU/ml
N/A N=216 VillageWhere: Innovative Mobile Technology for Youth With Conduct Disorder and Their Parents
Child Behavior Disorders
Primary: Child Behavior Checklist (CBCL) — 10.73; 11.45; 7.88; 7.49 score on a scale
Phase 3 N=50 Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors
Trichotillomania · Skin-Picking
Primary: NIMH Trichotillomania Symptom Severity Scale (NIMH-TSS) — 12.38; 10.63 score on a scale
Phase 4 N=85 Advancing Personalized Antidepressant Treatment Using PET/MRI
Depression
Primary: Change From Baseline in Hamilton Depression Rating Scale at 8 Weeks — 11.81; 9.41 score on a scale
Phase 3 N=19 A Study to Assess Efficacy and Safety of RESP301 Plus Standard of Care (SOC) Compared to SOC Alone in Hospitalized Participants With COVID-19
COVID-19
Primary: Number of Participants Who Progress by at Least One Level Higher on the Modified WHO Ordinal Scale — 0; 0; 0; 0 Participants
Phase 2 N=144 Efficacy and Safety of Dexamethasone Nanoparticles Eye Drops in Diabetic Macular Edema
Diabetic Macular Edema
Primary: Mean Change in Early Treatment of Diabetic Retinopathy Study (ETDRS) Best-corrected Visual Acuity (BCVA) — 2.62; 1.04 ETDRS BCVA Letters
Phase 2 N=274 This Study is Done in Patients With Plaque Psoriasis and Tests How Well They Tolerate BI 730357 and How Effective it is
Psoriasis
Primary: Number of Patients Who Achieved Psoriasis Area Severity Index Score (PASI) 75 at Week 12 — 0; 2; 3; 4 Participants — p=0.3091
Phase 2 N=30 A Study to Compare ORMD-0801 Once Daily to ORMD-0801 Three Times Daily in Subjects With Type 1 Diabetes
Type 1 Diabetes
Primary: Average Exogenous Basal Insulin Compared to Baseline (Placebo) — 27.28; 25.84; 27.32; NA mg/dL — p=<0.9223
N/A N=523 Wood Stove Interventions and Child Respiratory Health
Lower Tract Respiratory Infection
Primary: Number of Participants With at Least One LRTI During Follow-up Period — 16; 20; 17; 138 Participants — p=0.68
N/A N=9 Translational Control of Anabolic Resistance in Aging Muscle
Physical Inactivity
Primary: Lean Mass — 403 grams
N/A N=110 Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Preeclampsia · Hypotension
Primary: The Umbilical Artery pH — 7.22; 7.20 pH — p=.38
Phase 3 N=623 Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) in Adults With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Treatment-naïve Nonsmall Cell Lung Cancer (NSCLC) (MK-7902-007/E7080-G000-314/LEAP-007)
Non-small Cell Lung Cancer
Primary: Progression-free Survival (PFS) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) — 6.6; 4.2 Months — p=0.00624
N/A N=30 Treatments for Improving Mood in Depressed Teens-3
Depression
Primary: Acceptability — 11; 13 Participants
Phase 2 N=44 Investigating Cabozantinib in Patients With Refractory Metastatic Colorectal Cancer
Colorectal Cancer
Primary: 12-Week Progression Free Survival — 18 Participants