65,437 trials
Sphingomyelin Lipidosis
Primary: Percent Predicted (% Predicted) Hemoglobin (Hb) and Altitude-Adjusted Diffusing Capacity of the Lung for Carbon Monoxide (DLco) at Baseline — 48.45; 49.44 % Predicted DLco
Pyruvate Kinase Deficiency · Anemia, Hemolytic
Primary: Percentage of Participants Achieving a Hemoglobin (Hb) Response (HR) — 0; 40.0 percentage of participants — p=<0.0001
Short Bowel Syndrome
Primary: Number of Participants With Treatment-emergent Adverse Events (TEAEs) — 7; 2 Participants
COPD Exacerbation
Primary: Number of Moderate to Severe Exacerbation (Defined as Requiring Treatment With Systemic Corticosteroids and/or Antibiotics in the Community or Hospital or…
Untreated Adult Acute Myeloid Leukemia
Primary: Number of Participants With a Complete Response — 5; 5; 10; 0 Participants
Depressive Disorder, Treatment-Resistant
Primary: Change From Baseline in Montgomery Asberg Depression Rating Scale (MADRS) Total Score to the End of Double-blind Treatment Phase (Day 28) — -10.1; -8.1 Units on a Scale…
Gastric Cancer
Primary: Progression-Free Survival (PFS) — 9.5; 7.4 months — p=0.0727
Treatment Resistant Depression · Major Depressive Disorder · Treatment-Refractory Depression
Primary: Psychological Well-Being — 34.7; 35.0; 34.8; 33.1 t-score — p=0.010
Parkinson's Disease
Primary: Change in Motor MDS-UPDRS Score From Baseline at Week 12 — 1.4; -0.9; -1.2 score on a scale — p=0.3656
Preoxygenation
Primary: Preoxygenation Duration — 3.6; NA; NA minutes
Tourette Syndrome · Chronic Tic Disorder
Primary: Change in Global Severity of Tics and Clinical Condition as Measured by YGTSS — 20.19; 25.82 score on a scale
B Acute Lymphoblastic Leukemia · B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 · B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Primary: Complete Response (CR or CRi) — 0 proportion of participants
Systemic Sclerosis
Primary: Change in Modified Rodnan Skin Score (MRSS) — -10; -3.0 units on a scale
Surgical Site Infection · Vancomycin
Primary: Pharmacokinetics Analysis: V˅c — 2.56; 1.14 L
Post-Traumatic Stress Disorder
Primary: PTSD Symptoms — 10.02; 10.87; 15.12; 10.78 units on a scale