Phase 4 N=26 Gabapentin vs Chlordiazepoxide for Ambulatory Alcohol Withdrawal
Alcohol Withdrawal
Primary: Epworth Sleepiness Scale (ESS) — 6.35; 2.65 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=164 A Study to Evaluate the Safety and Immunogenicity of Oral Polio Vaccine Type 2 in Infants and Children
Adverse Event Following Immunisation
Primary: Number of Subjects Experiencing SAEs, Severe AEs (Grade 3), and/or IMEs — 0; 1 Participants
Phase 4 N=112 Sequential Multiple Assignment Treatment for Bipolar Disorder
Bipolar I Disorder · Bipolar II Disorder
Primary: Bipolar Inventory of Symptoms Scale (BISS) — -0.31; -0.41; 0.15; -0.38 calculated mean scale score
Phase 4 N=16 Comparing Bronchodilation of Symbicort With and Without Valved Holding Chamber (Aerochamber Plus)
Asthma
Primary: The Mean Area Under the Curve (AUC) of Forced Expiratory Volume in One Second (FEV-1) Over 12 Hours, Measured (BL), 5, 10, 15, 60, 120, 240, 480, 720 Minutes. The Unit…
Phase 4 N=44 Neurobehavioral Substrates of Propranolol's Effects on Drug Cue Reactivity
Cigarette Smoking
Primary: BOLD Activation to Smoking Cues - Amygdala — 0.002471; 0.077325; 0.009450; 0.090345 Percent Signal Change — p=.019
Phase 4 N=42 The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation
Nasal Obstruction
Primary: Nasal Obstruction as Measured by Nasal Obstruction Symptom Evaluation (NOSE) Scores Following Therapy With Treatment (Triamcinolone Acetonide) and Placebo (Ayr Saline…
Phase 4 N=192 Impact of Propofol Reduction in Anesthesia Induction
Propofol Adverse Reaction · Anesthesia
Primary: Systolic Blood Pressure Variation — 26; 23; 18; 22 percentage of variation
Phase 4 N=320 Ibuprofen Plus Metaxolone, Tizanidine, or Baclofen for Low Back Pain
Low Back Pain
Primary: Change in Functional Impairment as Measured by the Roland Morris Disability Questionnaire (RMDQ) — 10.1; 11.2; 10.6; 11.1 units on a scale
Phase 4 N=179 Smoking Tobacco and Drinking Study
Smoking · Heavy Episodic Drinking
Primary: Number of Participants With Reported 7-day Point Prevalence Abstinence at 3 Months — 3; 4 Participants
Phase 4 N=64 Use of On-Q Pump for Pain Post C-Section
Pain
Primary: Change in Pain Scores During Cough From Baseline — 4; 1; 20.5; 10 score on a scale
Phase 4 N=30 Examining the Effects of Antipsychotic Medications on Insulin Sensitivity
Diabetes
Primary: Change in Glucose Disposition — 1.18; 1.42 ratio of post/pre values — p=0.042
Phase 4 N=48 Hyperosmolar Saline Irrigation Fluid in Arthroscopic Knee Surgery
Arthroscopic Knee Surgery
Primary: Fluid Extravasation — 1.8; 1.2 centimeters
Phase 4 N=84 Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid Arthritis
Rheumatoid Arthritis
Primary: Change From Baseline in Rheumatoid Arthritis Impact of Disease Total Score at Week 24 — -2.4 score on a scale
Phase 4 N=10 Use of Sublingual Tacrolimus in Adult Blood and Marrow Transplant Patients
Immunosuppression · Stem Cell Transplant · Bone Marrow Transplant
Primary: Median Tacrolimus Sublingual Trough Level — 11.3 ng/mL
Phase 4 N=29 Neuroimaging of Anesthetic Modulation of Human Consciousness
Healthy
Primary: Change From Baseline in Blood Oxygen Level Dependent (BOLD) Response to Sensory Stimuli During Sedation — -0.349 percentage of BOLD signal change — p=<0.0001