65,437 trials
Pulmonary Disease, Chronic Obstructive
Primary: Time to First Moderate or Severe Chronic Obstructive Pulmonary Disease (COPD) Exacerbation Over the 12 Month Study Period — NA; NA Months
Primary Hyperoxaluria
Primary: Change From Baseline in Plasma Oxalate Concentration After 52 Weeks of Treatment — 14.8; 14.4; -0.71; 2.35 micromole/liter
Asthma
Primary: Categorized Percent Reduction From Baseline in the Daily OCS Dose While Not Losing Asthma Control — 40; 35; 5; 4 Participants — p=0.434
Heart Failure
Primary: Change in Pulmonary Artery Diastolic Pressure From Baseline to End of Treatment Period (Defined as Average of Pulmonary Artery Diastolic Pressure Measurements Between…
Asthma · Children
Primary: Asthma Control Test/Childhood Asthma Control Test at 12-months — 21.23; 20.58 score on a scale
Pneumococcal Infections
Primary: Percentage of Participants With a Solicited Injection-Site Adverse Event Following Vaccination With V114 or Prevnar 13™ — 9.4; 5.9; 10.3; 6.4 Percentage of Participants
Adrenal Insufficiency · Cirrhosis · Spur Cell Anemia
Primary: Number of Participants With Cholesterol Esterification Deficiency — 10; 11 Participants
Duchenne Muscular Dystrophy
Primary: Number of Participants With Treatment Emergent Adverse Events (TEAEs), Serious Adverse Events (SAEs), and TEAEs Leading to Discontinuation From Study Drug — 9; 6; 0; 1…
Dental Caries in Children · Health Behavior · Healthcare Disparities
Primary: Parent-reported Tooth Brushing Frequency — 1; 1; 12; 15 Participants
Opioid-use Disorder
Primary: Successful Vivitrol Induction — 10 Participants
Prosthetic Joint Infection
Primary: Safety Evaluations: Number and Frequency of Adverse Events Among Participants — 14; 14; 14; 14 Participants
Primary Hyperoxaluria
Primary: Change in Pre Dialysis Plasma Oxalate (Total Plasma Oxalate) Level During Treatment With OC5 Compared With Baseline. — 147.57; 11.34; 7.46; -5.68 μmol/L
Schizophrenia
Primary: Time to Relapse During the Double-Blind (DB) Phase — NA; NA Days
Stress Disorders, Post-Traumatic
Primary: Change From Baseline in Clinician-Administered Post-traumatic Stress Disorder (PTSD) Scale for Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5)…
Cystic Fibrosis
Primary: Part 1: Absolute Change From Baseline in MRI Global Chest Score at Week 48 — -0.3; -1.7 score on a scale