65,437 trials
Carnitine Palmitoyltransferase (CPT I or CPT II) Deficiency · Very Long Chain Acyl-CoA Dehydrogenase (VLCAD) Deficiency · Long-chain 3-hydroxy-acyl-CoA Dehydrogenase (LCHAD) Deficiency
Primary: Annualized LC-FAOD Major Clinical Events (MCEs) Rate: 18 Months Pre- and Entire UX007 Period Comparison for UX007-CL201-Rollover Cohort — 1.76; 1.00 events/year — p=0.0347
Anemia · Cancer
Primary: The Median Hb Change From Baseline to Week 12 — 2.35; 1.5; 0.5 gm/dl
Postural Orthostatic Tachycardia Syndrome
Primary: Plasma Volume — 2805; 3032; 2362; 2633 mL
Heavy Menstrual Bleeding · Menorrhagia · Uterine Fibroids
Primary: Change in Self-Reported Menorrhagia Scores — 59.1; 25.4 score on a scale — p=0.11
Anxiety
Primary: Baseline State-Trait Anxiety Inventory (STAI) — 53.1; 47.7; 53.2; 43.3 score on a scale
Zika · Dengue · Malaria
Primary: Number of Differentially Expressed Genes Between Bitten (Case) Versus Unbitten (Control) Skin for Each of the Three Vector Groups — 18; NA; 1; NA number of…
Postoperative Pain · Pregnancy · Obesity
Primary: Morphine Equivalents 0-24 Hours (Mgs) — 54; 38; 32; 45 Morphine equivalents (mg) — p=.05
Out-of-Hospital Cardiac Arrest
Primary: Number of Participants Who Survived Up To Hospital Discharge — 24; 40 Participants
Epilepsy
Primary: The Percentage of Subjects Completing 52 Weeks of Adjunctive Therapy During the Maintenance Phase [Retention Rate]. — 2; 3 Participants
Atrial Fibrillation
Primary: Number of Participants That Achieved More Than or Equal to 50%, 80%, and 90% Factor XI Inhibition at Trough After the Third Dose (Day 91) at Different Dose Levels of…
Dedifferentiated Liposarcoma
Primary: Phase 3 Double Blind: Progression-free Survival (PFS) as Per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1 — 2.83; 2.07 Months — p=0.0114
Diabetes
Primary: Reduction in Rebound Hyperglycemia (Blood Glucose Levels Over 180 mg/dl) — 14; 3 Participants
Psoriatic Arthritis
Primary: Difference Between Secukinumab and Placebo in Terms of Joint Synovitis as Measured by the Power Doppler Ultrasonography (PDUS) Global OMERACT-EULAR Synovitis Score…
Malignant Bone Tumors
Primary: Change in Bone Mineral Density (Tb. BMD) — 4.5; -39.3; -8.7; -54.7 mg/cm^3
Pneumonia · Aging
Primary: Pneumococcal-specific Antibody Responses — 72.1; 79.4; 128.9; 120.9 log2 titer