65,437 trials
Healthy · Obesity · Insulin Sensitivity
Primary: Mitochondrial Function in Circulating Cells and Muscle Tissue in Young Women — 26.48; 30.46; 120.04; 140.43 pmol O2/min per 400K cells
Multiple Myeloma
Primary: Fraction of Patients (n=3) for Whom a sdAb Could be Generated That Binds to the Idiotype of the Paraprotein. — 2 Participants
Liver Disease · Hepatitis D
Primary: Number of Participants With Decline of Hepatitis D Virus (HDV) RNA Viral Titer of >2 Logs — 18 Participants
Acute Lymphocytic Leukemia · Acute Myelogenous Leukemia · Burkitt's Lymphoma
Primary: Percentage of Participants With Progression Free Survival (PFS) — 35.0; 41.1 percentage of participants — p=0.4092
Chronic Heart Failure With Reduced Systolic Function
Primary: Difference in the Average of the 6- and 12-week Mean N-terminal Pro B-type Natriuretic Peptide (NTproBNP). — 1133; 1191 pg/dL
Tuberculosis, Pulmonary · Tuberculosis, Multidrug Resistant · Extensively Drug-Resistant Tuberculosis
Primary: Percentage of Participants Who Achieved Sputum Culture Conversion (SCC) Using the Mycobacteria Growth Indicator Tube (MGIT) System — 45.4; 41.9; 29.6 percentage of…
Mitral Valve Regurgitation
Primary: Number of Participants With Major Adverse Events (MAE) — 10 Participants
Acne Vulgaris
Primary: Percentage of Participants Achieving an IGA Score of Clear or Almost Clear and a Score ≥2 Grades Less Than Baseline — 25.4; 14.7 percentage of participants
Hearing Loss
Primary: Consonant-Nucleus-Consonant (CNC) Word Recognition in Quiet: Percentage of Total Words Correctly Recognized. — 71.2; 81 percentage of total words correct — p=<0.001
COVID-19 Pneumonia, Impaired Respiratory Function
Primary: APACHE II Severity of Disease Score on Day 15 or on the Day of Discharge (Whichever is Earlier) — 8.7; 8.6 Score on a scale — p=0.467
Pneumonia · Blood Stream Infection
Primary: Mortality — 92; 78; 122; 133 Participants — p=0.21
Renal Failure
Primary: Number of Participants With Composite Endpoint of Graft Survival (Non-death Censored) and Biopsy Proven Acute Rejection at 1 Year — 40; 19; 38; 19 Participants
Ovarian Cancer
Primary: Overall Response Rate — 1; 6; 4; 18 Participants
Pancreatic Cancer
Primary: Change in 400-meter Walk Time — 212.7; 194.3; 204 s
Acute Promyelocytic Leukemia
Primary: To Determine the Rate of Molecular Remission