N/A N=60 Non-invasive Cooling of Subcutaneous Fat
Fat Disorder
Primary: Change in Fat Layer Thickness of the Treated Flank — -18.7; -22.6; -17.8; -17.5 percent fat layer change
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=36 Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver Metastases
Metastatic Triple Negative Breast Cancer · Metastatic Colorectal Cancer
Primary: Number of Participants Who Experienced a Dose-Limiting Toxicity (DLT) — 0; 3 Participants
Phase 2 N=48 Omacetaxine in Patients With Intermediate-1 and Higher Risk Myelodysplastic Syndrome (MDS) Post Hypomethylating Agent (HMA) Failure
Leukemia
Primary: Overall Survival (OS) — 7.5 Months
Phase 3 N=258 Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt
Glaucoma · Open Angle or Ocular Hypertension
Primary: Intraocular Pressure (IOP) at Week 12 — 20.6; 20.8 mmHg
N/A N=72 Hemodialysis Reliable Outflow (HeRO) Vascular Access Patency Study
Renal Failure Chronic Requiring Hemodialysis
Primary: Percentage of Patients With Primary Patency — 48.2; 47.0; 30.6; 34.8 percentage of participants patent
N/A N=15 Alternating Pressure Overlay on Weight Bearing Tissue Tolerance in People With Spinal Cord Injury
Spinal Cord Injuries · Pressure Ulcer
Primary: Sacral Skin Blood Flow During Supine Lying — 12.65; 15.54; 11.96 arbitrary unit
Phase 2 N=86 Safety and Efficacy Study of Subcutaneous Belimumab and Intravenous Rituximab Co-administration in Subjects With Primary Sjogren's Syndrome
Sjogren's Syndrome
Primary: Number of Participants With Serious Adverse Events (SAE) and Non-serious AEs (Non-SAE) — 0; 3; 2; 4 Participants
Phase 4 N=48 VAccination to Improve Clinical outComes in Heart Failure Trial: a Feasibility Study (VACC-HeFT)
Chronic Heart Failure
Primary: Number of Participants With 4 Fold Rise in Serum Antibody Concentration of A/H1N1 Vaccine Antigens — 11; 12 Participants — p=0.89
N/A N=500 A Proactive Walking Trial to Reduce Pain in Black Veterans
Musculoskeletal Pain
Primary: 30% Improvement in Physical Functioning as Assessed by the Roland Morris Disability Questionnaire [RMDQ]) at 6 Months — 38; 46 participants w/ >= 30% improvement — p=0.09
N/A N=15 CoolSculpting Treatment in the Upper Arms
Body Fat Disorder
Primary: Proportion of Correctly Identified Pre-treatment Photos — 26 photos
Phase 3 N=1,594 In-vivo Efficacy Study of Patient Pre-operative Preps
Bacterial Reduction on Skin Flora Post-product Application
Primary: Responder Rate — 178; 167; 175; 0 Participants
Phase 2 N=107 An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery
Postoperative Pain
Primary: Pain Intensity (PI) — 5.16; 6.43; 5.16 score on a scale (time-normalized AUC) — p=0.012
Phase 4 N=106 PPIs and Gastroesophageal Varices in Liver Cirrhosis (PPIs: Proton Pump Inhibitors)
Liver Cirrhosis · Hypertension, Portal
Primary: Variceal Bleeding Events — 3; 3 Participants
Phase 3 N=46 Lamotrigine in Reducing Psychologic Side-Effect of Perioperative Ketamine
Reducing Psychological Side Effects of Ketamine
Primary: Psychologic Side-effects — 4; 4 score on a scale — p=0.08
Phase 2 N=15 Sonothrombolysis in Patients With STEMI
ST-segment Elevation Myocardial Infarction
Primary: Number of Participants With Spontaneous Reperfusion — 2 participants