Phase 2 N=13 Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension
Pulmonary Hypertension · Sickle Cell Disease · Thalassemia
Primary: Erythrocyte Glutamine/Glutamate Ratio at 8 Weeks — 2.40 Ratio
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=300 Infant TB Infection Prevention Study
Tuberculosis
Primary: Mycobacterium Tuberculosis (MTB) Infection — 10; 18 participants
Phase 2 N=12 Safety and Efficacy of Oral Treprostinil in the Treatment of Calcinosis in Patients With Systemic Sclerosis
Systemic Sclerosis · Calcinosis
Primary: Number of Participants With Treatment-related Adverse Events Following Treatment With Oral Treprostinil — 11 Participants
N/A N=107 Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Joint Pain · Trouble Balancing
Primary: Patient Reported Balance — 3.0; 2.1 units on a scale
Phase 2 N=40 Stimulant Oxytocin Study
Stimulant Use & Co-occuring Opioid Use Disorders
Primary: Number of Participants With Stimulant Positive Drug Screen — 9; 12; 9; 10 Participants
Phase 3 N=2,060 Preventing Caries in Preschoolers: Testing a Unique Service Delivery Model in American Indian Head Start Programs
Fluoride Varnish and Oral Health Promotion · Usual Care
Primary: Evaluation of Decayed, Missing, and Filled Tooth Surfaces (Dmfs) at Baseline — 19.9; 22.8 dmfs
N/A N=75 Testing of a Valsalva Assist Device (VAD) in Healthy Volunteers Performing a Valsalva Manoeuvre
SVT · Vagal Bradycardia
Primary: Assessing Heart Rate During the Supine and Modified VM and Assessing Heart Rate While Using the VAD and Manometer — 33.6; 25.9; 28.7; 30.8 beat per minute — p=<0.001
Phase 2 N=50 Study Of Weight-Based Versus Standard Dose Enoxaparin Thromboprophylaxis In High-Risk Hospitalized Cancer Patients
Venous Thormboembolism
Primary: Total Number of Venous Thromboembolic Events (VTE) in Standard Dose Enoxaparin Arm at 17 Days — 2 participants
Phase 4 N=11 Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms
Myopathic Symptoms
Primary: Number of Participants With Reduction in Myopathic Pain — 4; 4 Participants
Phase 3 N=1,134 A Study of Napabucasin Plus Nab-Paclitaxel With Gemcitabine in Adult Patients With Metastatic Pancreatic Adenocarcinoma
Carcinoma, Pancreatic Ductal
Primary: Overall Survival — 11.43; 11.73 Months
N/A N=362 Post Marketing Surveillance Study For Sayana®
Product Surveillance, Postmarketing
Primary: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) — 81; 1 Participants
N/A N=71 Efficacy of Surgical Treatment by Different Pedicle Screw Systems in Pediatric Neuromuscular Spinal Deformity
Neuromuscular Diseases · Neuromuscular Scoliosis
Primary: First Scoliotic Curve — 71.4029 degrees
Phase 3 N=138 Ambulatory Blood Pressure Monitoring in Oral Testosterone Undecanoate (TU, LPCN 1021) Treated Hypogonadal Men
Hypogonadism, Male
Primary: Change in Ambulatory Blood Pressure Monitoring (ABPM)-Measured Average 24-hour Systolic Blood Pressure (SBP) — 3.8 mmHg
Phase 4 N=1,561 MAST Trial: Multi-modal Analgesic Strategies in Trauma
Nonspecific Pain Post Traumatic Injury
Primary: Opioid Use Per Day — 48; 34 MME per day
Phase 2 N=4,748 Efficacy and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-like Particle Vaccine in Adults
Healthy Volunteers
Primary: Number of Participants With Moderate or Severe Acute Gastroenteritis (AGE) Occurring for >7 Days After Dosing Due to GI.1 or GII.4 Norovirus Strains (Excluding…