65,437 trials
Recurrent Fallopian Tube Carcinoma · Recurrent Ovarian Carcinoma · Recurrent Primary Peritoneal Carcinoma
Primary: Objective Response Rate (ORR) Using RECIST 1.1 — 3 patients
Total Knee Replacement · Total Knee Arthroplasty · Pain
Primary: Average Knee Pain While Walking — 3.70; 4.14 Scores on a scale
Postural Tachycardia Syndrome
Primary: Orthostatic Heart Rate (HR) Change — 23; 28; 34; 39 beats per minute — p=<0.001
Cardiovascular Diseases · Mood Disorders · Inflammation
Primary: Circulating Serum Interleukin-6 (IL-6) — 1.13; 1.01; 0.88; 0.81 pg/mL — p=0.59
Osteoarthritis
Primary: Change From Baseline in Cartilage Thickness of the cMTFC as Assessed by qMRI on the Target Knee to Week 52 — -0.06791; -0.09693; -0.08545; -0.11562 mm — p=0.165
Pain
Primary: Analgesia: Change From Baseline in Pain Tolerance and Threshold as Measured by the Cold Pressor Test — 9.7; 2.2; 2.1; 1.2 Seconds
Nasal Polyps · Chronic Rhinosinusitis
Primary: Change From Baseline in Nasal Polyp Score (NPS) — -0.17; -0.85; -0.26; -1.06 Sore on a scale
Tuberculosis
Primary: New Infection With Mycobacterium Tuberculosis — 19; 18 Participants
Adverse Effect of Radiation Therapy
Primary: Mean Best Corrected Visual Acuity (BCVA) in Patients Treated With Intravitreal Aflibercept Injections for the Management of Radiation Maculopathy. — 0.425; 0.548 Log MAR…
Prostate Cancer Metastatic
Primary: Part B: Progression Free Survival (PFS) — 3.78; 2.83 months
Moderate to Severe Plaque Psoriasis
Primary: • The Proportion (Number) of Patients in Each Study Arm Who Achieved a PASI 75 at Week 12 of Treatment — 66; 70; 0 Participants
Type 2 Diabetes Mellitus
Primary: Change From Baseline in Hemoglobin A1c (HbA1c) at Week 26 — 0.06; -0.70 percentage HbA1c — p=< 0.0001
Head Lice Infestation
Primary: Percentage of Hatched Eggs Pre Treatment Relative to Post Treatment — -92.9; -42.3 Percent hatched eggs post versus pre Rx
Major Depressive Disorder
Primary: Change in Investigator-administered MADRS Total Score From Baseline BTRX-246040 and Placebo — -15.0; -13.6 Change in score on a scale from baseline — p=0.5939
Type 2 Diabetes Mellitus
Primary: Change From Baseline in Hemoglobin A1c (HbA1c) at Week 26 — -0.29; -0.77 percentage of HbA1c — p=< 0.0001