Phase 4 N=198 Effects of Sublingual and Transdermal Administration of Nitroglycerin for Coronary CT Angiography on Image Quality
Coronary Artery Disease
Primary: Coronary Artery Diameter Change — 1.14; 1.13; 1.15 Fold change
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=70 Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade?
Neuromuscular Block
Primary: BIS Signal Variability Using the Measured Standard Deviation During the Maintenance Phase of Anesthesia — 7.6; 7.8 units on a scale — p=0.651
Phase 4 N=106 The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.
Strabismus
Primary: Breath Duration — 2.14; 2.18; 2.26; 2.15 seconds
Phase 4 N=15 QR-Bromocriptine as an Adjunct to Insulin and Metformin in the Treatment of Type 2 Diabetes
Diabetes Mellitus, Type 2
Primary: Change in A1c — 9.74; 7.98 percent HbA1c — p=0.004
Phase 4 N=159 A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes
Type 2 Diabetes
Primary: Change From Baseline in Hemoglobin A1c (HbA1c) — 0.06; -1.45 percentage of HbA1c — p=<0.001
Phase 4 N=81 Trial of High Dose vs. Standard Dose Influenza Vaccine in Inflammatory Bowel Disease Patients
Inflammatory Bowel Disease (IBD)
Primary: Measure Antibody Concentrations in Immunosuppressed IBD Patients Who Receive High Dose and Standard of Care Dose Influenza Vaccine — 160; 160; 160; 160 Antibody Titer
Phase 4 N=1,291 Azithromycin - Ivermectin Mass Drug Administration for Skin Disease
Scabies · Yaws · Impetigo
Primary: Impetigo Prevalence at 12 Months — 79; 66; 20; 12 Cases of impetigo
Phase 4 N=118 NextStep:Study to Evaluate Safety,Efficacy & Tolerability of Rivastigmine Patch in Mild to Moderate Alzheimer's Patients.
Mild to Moderate Alzheimer's Disease
Primary: MMSE Total Score: Change From Baseline to Week 8 and Week 24 (Full Analysis Set) — 17.33; 0.29; -0.36 scores on a scale — p=0.1750
Phase 4 N=80 Recovery and Analgesia After Surgery for Gynecological Cancer
Gynecological Cancer
Primary: Length of Stay — 4.3; 3.3 days
Phase 4 N=30 Naturalistic Study, Comparison of Divalproex Extended Release (ER) and Quetiapine for Adults With Acute Mania or Mixed Episodes
Bipolar Disorder
Primary: Primary Measure: Young Mania Rating Scale (YMRS) Primary Endpoint: Day 7 — 14.8; 13.9 units on a scale
Phase 4 N=30 Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome
Fragile X Syndrome · Genetic Diseases
Primary: Expressive Language Sample Composite Score in the Home — 39.63; 42.47 score on a scale
Phase 4 N=86 Pharmacoeconomics and Related Patient Outcomes of Multi-dose Intravenous Acetaminophen (OFIRMEV)
Prostatectomy · Pain
Primary: Post Anesthesia Care Unit Length of Stay — 124; 132 minutes
Phase 4 N=57 Belatacept Compared to Tacrolimus in Deceased Donor Renal Transplant Recipients
Implant or Graft; Rejection
Primary: Number of Participants With Delayed Graft Function (DGF) — 12; 15 Participants
Phase 4 N=10 Transdermal Patch CVD 2000: The Effect of Heat on Fentanyl Release From Fentanyl TDSs in Healthy Adults
Peer Review, Research
Primary: Partial Area Under the Curve (AUC) Attained With Early and Late Heat in Each of the Three Fentanyl TDSs (Reference and Generic) — 2.2; 1.7; 2.1; 2.7 h*ng/mL
Phase 4 N=50 Cost Comparison Study of Darbepoetin Versus Epoetin Therapy to Treat Anemia in Hemodialysis Patients
Anemia · Chronic Kidney Disease
Primary: Cost of Erythropoiesis Stimulating Agent — 4178.70; 2302.92 dollars Canadian