65,437 trials
Epilepsy
Primary: Percentage of Participants in Each Treatment Group Achieving Seizure Activity Cessation Within 2 Minutes and no Recurrent Seizure Within 2 Hours — 62.5; 42.5; 65.8; 65.8…
Rectal Cancer
Primary: Percentage of Patients With Complete Tumor Regression Rate (TRG1) — 12.5; 50 percentage of participants
Mucopolysaccharidoses
Primary: Carotid Intima-media Thickness, Measured in Millimeters — 0.44; 0.52; 0.56 mm
Malignant Solid Tumour · Breast Cancer Nos Metastatic Recurrent · Neuropathy
Primary: Maximum Tolerated Dose (MTD) in Participants With Any Solid Tumor (Phase Ib) — 1.4; 600 milligrams per square meter (mg/m2)
Skin Laxity · Lipodystrophy
Primary: Number of Participants With a Reduction of Submental Skin Area ≥ 20 mm^2 — 49 Participants
Respiratory Failure
Primary: Comparable Level of Gas Exchange (Measured as Partial Pressure of Carbon Dioxide (CO2) in Arterial, Venous or Capillary Blood) — 37; 33.3 mEq/L
Multiple Sclerosis, Relapsing-Remitting
Primary: Percentage of Participants With No Evidence of Disease Activity (NEDA) as Per Protocol Defined Events During a 96-Week Period — 74.8 Percentage of Participants
Vitamin D Deficiency
Primary: Safety of a Single High-dose of Oral Cholecalciferol to Treat a Vitamin D Deficiency in Children With Cystic Fibrosis — 9.57; 9.47 mg/dL
Heart Failure
Primary: Sustained Virologic Response After Treatment — 24 Participants
Overactive Bladder
Primary: Number of Participants With the Indicated Type of Treatment-emergent Adverse Event — 171; 126; 59; 46 participants
Brain Cancer
Primary: Overall Survival (OS) — 13.40; 14.88 Months — p=0.0037
Carcinoma, Hepatocellular · Metastatic Colorectal Cancer
Primary: To Assess the Safety and Tolerability of Treatment With BTG-002814 — 8; 4 Participants
Malocclusion
Primary: Total Treatment Time — 197.4167; 225.7; 326.9355; 294.1111 days
Dry Eye Syndromes
Primary: Change in Tear Lipid Layer Thickness — 4.8; 8.8 nm
Nonhemorrhagic Ischemic Stroke · Motor Function
Primary: Mean Change From Baseline in Total Simplified-STroke Rehabilitation Assessment of Movement (S-STREAM) Score in Participants Obtained Between 24 and 48 Hours of a…