N/A N=46 Quadratus Lumborum Block for Analgesia Following Hip Arthroscopy
Surgery
Primary: Opioid Consumption — 8.1; 11.3 Morphine Milligram Equivalents
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=70 Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes
Arthroplasty, Replacement, Knee
Primary: Opioid Consumption After Surgery — 192; 144 Morphine Equivalents (ME) — p=.978
Phase 4 N=68 Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant
HIV · Hepatitis C · Cirrhosis
Primary: Number of Participants With Sustained Virologic Response (SVR) — 38; 25 Participants
Phase 2 N=128 A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN)
Prurigo Nodularis
Primary: Average Visual Analog Scale at Baseline — 7.92; 7.88 Units on a scale
N/A N=1,485 Effect of a Patient-Centered Decision App on TOLAC
Pregnancy · Repeat Cesarean Section · Vaginal Births After Cesarean
Primary: Number of Participants Who Underwent a Trial of Labor After Cesarean (TOLAC) Delivery — 315; 338 Participants
Phase 3 N=181 A Study To Find Out How Fesoterodine Works In Children Aged 6 To 17 Years With Bladder Overactivity Caused By A Neurological Condition
Urinary Bladder, Neurogenic
Primary: Change From Baseline in Maximum Cystometric Bladder Capacity at Week 12: Active Comparator Phase/Efficacy Phase — 58.12; 83.36; 87.17; 23.49 milliliter — p=0.0001
Phase 2 N=120 Anastrozole or Fulvestrant in Treating Postmenopausal Patients With Breast Cancer
Breast Cancer
Primary: Objective Response Rate (ORR) Determined by Clinical Palpation — 58.9; 53.8 percentage of participants
N/A N=30 Seating System for Scoliosis in Non-ambulatory Children With Cerebral Palsy: A Pilot Randomized Controlled Trial
Cerebral Palsy · Neuromuscular Scoliosis
Primary: Cobb Angle — 23.77; 26.31 degrees
Phase 4 N=30 Increased Cefazolin During Cesarean Delivery in Obese Population
Obesity · Obesity, Morbid · Pregnancy
Primary: Achievement of Minimal Inhibitory Concentrations Within Adipose and Serum Sampled at Time of Cesarean Delivery — 22.4; 9.6 mg/g
Phase 2 N=18 Phase I Dose Escalation of Monthly Intravenous Ra-223 Dichloride in Osteosarcoma
Sarcoma
Primary: Maximum Tolerated Dose (MTD) of Ra-223 Dichloride in Osteosarcoma — 100; 100 kBq/kg
Phase 2 N=41 Open Label Extension In Cancer Patients
Neoplasms · Bone Metastases
Primary: Change From Parent Study (A4091003 [NCT00545129]) Baseline in Brief Pain Inventory-Short Form (BPI-sf) Average Pain Score for at Weeks 4, 8, 16, 24, 40, 48, 56 and 64…
Phase 2 N=31 Cardiac Safety Study in Patients With HER2 + Breast Cancer
HER2 Positive Breast Cancer · Left Ventricular Function Systolic Dysfunction
Primary: Percentage of Patients Who Complete Planned Oncologic Therapy Without the Development of a Cardiac Event or Asymptomatic Worsening of Cardiac Function. — 27 Participants
Phase 3 N=8,588 Study to Assess the Efficacy and Safety of PT010 Relative to PT003 and PT009 in Subjects With Moderate to Very Severe COPD (Ethos)
COPD
Primary: Adjusted Rate of Moderate or Severe Exacerbations — 1.08; 1.07; 1.42; 1.24 Moderate or Severe Exacerbations — p=<0.0001
Phase 4 N=75 Sublingual Sufentanil vs Intravenous Fentanyl for Acute Pain in the Ambulatory Surgery Center
Pain · Pain, Acute · Anesthesia
Primary: Recovery Room Time — 73.0; 65.0 minutes
N/A N=17 Magnesium L-Threonate for the Enhancement of Learning and Memory in People With Dementia
Dementia · Alzheimer's Disease
Primary: Change From Baseline in Cognitive Function — -0.58; -1.73; -0.36; -0.07 units on a scale