Phase 4 N=192 Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial
Psoriatic Arthritis
Primary: Psoriatic Arthritis Disease Activity Score (PASDAS) — 4.7; 4.0; 3.6 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=757 A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease
Dry Eye Disease
Primary: Treatment-Emergent Serious Adverse Events (TE-SAEs) of Visual Acuity Decrease — 0; 0 Participants
N/A N=16 Enhancement of Behavioral and Cognitive Outcomes in Autism Spectrum Disorder Via Neurostimulation
Autism Spectrum Disorder
Primary: The Effects of rTMS on Reciprocal Social Awareness — 68; 79.667; 64.2; 74 total raw score (higher=worse)
Phase 2 N=52 Study of Chemotherapy With Cisplatin/Carboplatin, and Docetaxel With or Without Erlotinib in Patients With Head and Neck Squamous Cell Carcinomas Amenable for Surgical Resection
Head and Neck Cancer
Primary: Major Pathologic Response (MPR) Rate (Primary (Overall) Analysis) — 7; 10 participants
Early Phase 1 N=7 Safety and Tolerability of Cannabidiol Among Persons With Opioid Use Disorder Receiving Methadone or Buprenorphine
Addiction
Primary: Agitation Calmness Evaluation Scale (ACES) — 4; 4; 4; 4.07 score on a scale
Phase 4 N=34 Estrogen Variability and Irritability During the Menopause Transition
Menopause · Irritable Mood
Primary: Mean IDAS Ill Temper Scale Score Over Time — 6.19; 6.02 score on a scale — p=0.09
N/A N=73 Pilot Clinical Evaluation of a Microwave Imaging System for Breast Cancer Detection
Breast Cancer
Primary: Assess the Detectability Rate of Malignant and Benign Breast Lesions. — 56 Dominant Lesions - Malignant & Benign
N/A N=10 Peer Partners to Improve Physical Activity in Older Latino and Latina Adults With Parkinson's Disease.
Parkinson Disease
Primary: Acceptability of Intervention Measure (AIM) — 93 score on a scale
Phase 4 N=107 A Randomized Control Trial Assessing the Effect of Topical Tranexamic Acid on Risk of Hematoma in Breast Surgery
Hematoma Postoperative
Primary: Hematomas — 0; 1 hematomas — p=0.486
Phase 3 N=14,001 Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern
SARS-CoV-2 Infection · HIV Infections · COVID-19
Primary: Part A: Number of Participants With a First Occurrence of CDC-defined COVID-19 Starting 1 Day After Month 0 Dose Until Month 6 Dose in FAS Cohort Between Analysis Group…
N/A N=37 Online Singing Interventions for Postnatal Depression in Times of Social Isolation: a Single Arm Study
Postnatal Depression · Social Isolation
Primary: To Assess the Effectiveness of Online Group Singing Interventions on Symptoms of Postnatal Depression Using the Edinburgh Postnatal Depression Scale (EPDS) — 16.6; 11.2…
Phase 2 N=11 Evaluation of Safety, Efficacy and Pharmacodynamic Effect of Bertilimumab in Patients With Bullous Pemphigoid
Pemphigoid, Bullous
Primary: Number of Participants With Anti-Drug Antibodies — 0 Participants
Phase 3 N=751 A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities
Obesity · Overweight
Primary: Percent Change From Baseline in Body Weight — -20.2; -13.7 Percent change
Phase 2 N=46 CAN-DOSE Study: Cessation With Augmented Nicotine for Dual Use Of Smoking and E-cigarettes
Smoking Cessation · Electronic Cigarette Use · Cigarette Smoking
Primary: Days of Dual Use Abstinence — 3.8; 11.2; 6.9; 4.6 Days
Phase 2 N=55 A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
Knee Osteoarthritis
Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC-A) — 22.5; 18.6; 18.9; 18.2 Score on a scale — p=.006