Phase 1 N=58 A Study of Insulin Glargine (LY2963016) in Healthy Chinese Participants
Healthy
Primary: Pharmacokinetics (PK): Maximum Serum Concentration (Cmax) of Insulin Glargine and Lantus — 124; 129 picomole per liter (pmol/L)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=70 The Clinical Comparison of Somofilcon A 1 Day and Nelfilcon A Daily Disposable Contact Lenses
Ametropia
Primary: Subjective Comfort at Lens Dispensing — 90.9; 88.5 units on a scale
N/A N=248 Comparing the Efficacy of Reverse Hybrid Therapy and Concomitant Therapy
Helicobacter Pylori Infection
Primary: Number of Participants in Which H. Pylori Was Eradicated — 124; 121 participants
Phase 2 N=244 BEN-2001 in Parkinson Disease Patients With Excessive Daytime Sleepiness
Excessive Daytime Sleepiness · Parkinson Disease
Primary: Measurement of Sleepiness Using the Epworth Sleepiness Scale (ESS) at Baseline and Post Dose. — -4.34; -4.64; -3.46; -4.73 units on a scale — p=0.668
Phase 2 N=16 A Phase 2a Study of Modified Vaccinia Virus to Treat Sorafenib-naïve Advanced Liver Cancer
Hepatocellular Carinoma
Primary: Number of Participants With Radiographic Response — 4 Participants
N/A N=789 Enhancing Source Credibility in Tobacco Regulatory Communications
Cigarette Smoking Behavior
Primary: Quit Intentions — 2.73; 2.67; 2.58 score on a scale
N/A N=208 Home-based Delivery of the Contraceptive Implant in Postpartum Guatemalan Women
Postpartum
Primary: Number of Participants With Implant Use at Three Months — 28; 2 Participants
N/A N=327 Improving Follow-Up for Discharged Emergency Care Patients
General Medicine · Emergency Medicine · Mobile Health
Primary: Adherence to Follow-up Appointment — 30; 74 Participants — p=<0.001
Phase 2 N=11 CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial Lipodystrophy
Familial Partial Lipodystrophy · Nonalcoholic Steatohepatitis · NAFLD
Primary: Percent Change in Fasting Triglyceride Levels — 55.76 percentage of change from baseline
N/A N=731 Randomized Control Trial of Booster Seat Education Material to Increase Perceived Benefit Among Parents
Wounds and Injuries
Primary: Change in Perceived Safety Benefit of Booster Seats — 0.27; 0.15 Scores on a scale from 1 to 5 — p=0.002
Phase 4 N=1,275 Study of Oral Treatments for Hepatitis C
Chronic Hepatitis C
Primary: Sustained Virologic Response (SVR12) mITT With Imputation-Phase 1 and 2 EBR/GZR, SOF/LDV — 40; 516; 14; 335 Participants
Phase 3 N=495 A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne
Acne Vulgaris
Primary: Absolute Change From Baseline in the Inflammatory Lesion Count at Week 12 — 13.78; 10.64 Lesions — p=0.0051
N/A N=1,076 Improving Cardiac Arrest Diagnostic Accuracy of Emergency Medical Dispatchers
Cardiac Arrest
Primary: Number of Participants With Agonal Breathing — 176; 87 Participants
Phase 4 N=50 Lower Third Molar Removal With 2% and 4% Articaine
Impacted Third Molar Tooth · Adverse Reaction to Other Local Anesthetics
Primary: Onset of Anesthetic — 1.5; 1.5 minutes — p=0.192
N/A N=152 A Safety and Effectiveness Trial of Spinal Cord Stimulation of the Dorsal Root Ganglion for Chronic Lower Limb Pain
Chronic Lower Limb Pain
Primary: Primary Composite Endpoint - Treatment Success — 81.2; 55.7 percentage of subjects — p=<0.0001