Clinical Trial Search

Primary: Change From Baseline PTSD Checklist Civilian (PCL-C) at 1 Month — 1.30; 5.04 score on a scale

Primary: Number of Patients With Dose-limiting Toxicities, as Assessed by CTCAE v 4.0 — 0 Participants

Primary: Associative Memory Assessed by a Verbal Paired-Associate Test — 50.6; 50.78; 32.77; 30.25 percentage

Primary: Change in Erythrocyte Protoporphyrin Levels — 2314.6; 2240.4 µg/dL

Primary: Objective Tumor Response — 12.2; 31.4 percentage of participants

Primary: Insulin Sensitivity — 10.16; 8.45; 9.47; 5.96 M Value (mg/kg/min) — p=<0.025

Primary: Infant Weight-for-Length Z Scores — 0.43; 0.12 z-score — p=0.07

Primary: Adverse Events — 10; 5; 1; 0 Participants

Primary: Change From Baseline to Week 12 in the Percent Predicted Slow Vital Capacity (SVC) — -6.46; -4.97; -4.62; -4.58 percent predicted — p=0.1095

Primary: Change From Baseline to Week 26 in Pulmonary Vascular Resistance (PVR) — 0.46; 0.48 ratio — p=0.4239

Primary: Number of Participants With Dose-Limiting Toxicities (DLT) or DLT-equivalent in Part A, B, C, D and E — 1; 4; 0; 5 Participants

Primary: Number of Participants Who Were Alive at 1 Year Transplant Overall Survival — 130 Participants

Primary: Persistently Elevated Blood Pressures 7 Days Postpartum — 10; 23 Participants — p=0.03

Primary: Percentage of Participants With Objective Response (OR) Per the Lugano Classification According to Independent Radiology Review Committee (IRRC) in Cohort 1 — 91…

Primary: 30 Day Mortality — 36; 45 Participants