Phase 3 N=90 Pain Reduction With Intranasal Medications for Extremity Injuries
Pain · Traumatic Limb Injury
Primary: Difference From Baseline in Visual Analog Scale Pain Score — -30.6; -31.9 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=86 The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery
Postoperative Cognitive Dysfunction
Primary: Interleukin-6 Concentration in Peripheral Blood. — 27.2; 26.6; 104; 97.7 pg/ml
N/A N=30 Tolerability of Acthar for the Treatment of Multiple Sclerosis in Relapses (TAMS)
Relapsing Remitting Multiple Sclerosis
Primary: ARMS (Assessing Relapses in Multiple Sclerosis) ADL Scores (Activities of Daily Living) — 3.1; 4.9 score on a scale — p=0.003
Phase 4 N=154 A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age
Poliomyelitis
Primary: SAEs and AEs G3 — 0; 0 Participants
Phase 2 N=11 Topical Ruxolitinib for the Treatment of Vitiligo
Vitiligo
Primary: Percent Change in Vitiligo Area Severity Index (VASI) Score From Baseline to Week 20 — 23 percentage of change in VASI — p=0.02
Phase 2 N=26 Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and Hypertension
Diabetes Mellitus, Type 2 · Hypertension
Primary: Change From Study Baseline Over Time in Supine Systolic Blood Pressure — 130.2; 120.1; 128.6; -6.8 mmHg
N/A N=399 Pancreas Resection With and Without Drains
Pancreas Tumor · Pancreatitis
Primary: 60-day ≥ Grade II Complication Rate — 72; 76 Participants — p=0.804
N/A N=192 Involving Nursing Home Residents and Their Families in Acute Care Transfer Decisions
Chronic Disease · Acute Disease
Primary: Preparation for Decision Making — 39.59; 36.00 score on a scale — p=0.046
Phase 3 N=75 Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation
Labor Pain
Primary: Time to Achieve an Adequate Epidural Level for Labor Analgesia — 7.0; 11.0; 8.5 minutes
Phase 1 N=56 Oral Abuse Potential Study of Nalbuphine
Nalbuphine · Opioid Abuse
Primary: To Identify the Appropriate Low, Intermediarte, and High Doses of Nalbuphine Solution (Part A) to be Administered as Single Doses in the Treatment Phase of the Main…
Phase 3 N=83 Lifestyle Intervention and Testosterone Replacement in Obese Seniors
Obesity and Hypogonadism
Primary: Change in the Physical Performance Test — 4.6; 4.9 units on a scale — p=0.58
N/A N=24 A Clinical Study to Determine the Safety and Effectiveness of Dentinal Hypersensitivity Treatment With Two Different Toothbrushes
Dentin Sensitivity
Primary: Change From Baseline Air Challenge — -0.409; -0.917 Units on a scale
Phase 2 N=5 Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients
Treatment Resistant Depression
Primary: Cortical Excitability in the Dorsolateral Prefrontal Cortex (DLPFC) as Assessed by Transcranial Magnetic Stimulation-evoked Activity Detected by Electroencephalography…
N/A N=46 Is There Any Correlation Between Respiratory Variation Ratios of Internal Jugular Vein and Inferior Vena Cava?
Critically Ill
Primary: Ultrasonography (USG) Measurements — 1.80; 1.97; 1.22; 1.61 centimeter
Phase 2 N=130 Phase 2 Study of Gemcitabine or Gemcitabine + Enzastaurin in Participants With Advanced or Metastatic Pancreatic Cancer
Pancreatic Neoplasm
Primary: Overall Survival (OS) — 5.6; 5.1 months