6,678 trials
Type 1 Diabetes Mellitus
Primary: Part 1: Area Under the Curve (AUC) of Glucose Infusion Rate (GIR) From 0-6 Hours
Infections, Streptococcal
Primary: Number of Subjects With Antibody Concentrations Against Vaccine Pneumococcal Serotypes Greater Than or Equal to (≥) the Cut-off — 144; 155; 160; 52 Participants
Pneumococcal Pneumonia · Influenza
Primary: The Number of Patients With Positive Antibody Response in Serotype 23F of Pneumococcal Antibody. — 63; 59 Participants
End Stage Renal Disease (ESRD) · Chronic Kidney Disease (CKD) · Hemodialysis
Primary: Incidence of Failure on the Composite of Treated Biopsy-proven Acute Rejection (tBPAR) or Estimated Glomerular Filtration Rate (eGFR) < 50 mL/Min/1.73m2. — 489; 456…
Type 2 Diabetes
Primary: CD34+ Endothelial Progenitor Cells Number — 2.0; 2.8 % of Mononuclear Cells
Prophylaxis of Acute Mountain Sickness
Primary: Number of Participants With Acute Mountain Sickness as Measured by the Lake Louise Score — 21; 21 Participants
Plaque Psoriasis
Primary: Number of Participants Maintaining Psoriasis Area Severity Index Score (PASI) 75 at Week 36 — 4; 2 participants
Diphtheria-Tetanus-acellular Pertussis Vaccines
Primary: Antibody Concentrations Against Pertussis Toxoid Antigen (Anti-PT), Filamentous Haemagglutinin Antigen (Anti-FHA) and Pertactin Antigen (Anti-PRN) in Cord Blood Samples…
Relapsing Remitting Multiple Sclerosis
Primary: Annual Relapse Rate (ARR) — 0.290; 0.354 Relapses per year — p=0.3118
Sickle Cell Disease
Primary: Average Percent Hemoglobin (HbA) Decrement Per Day — 0.629; 0.659 %HbA per day — p=0.95
Smoking · Nicotine Addiction · Surgery
Primary: Smoking Status on the Day of Surgery (48-hour Point-prevalence Abstinence), by Self-report and Confirmed With Exhaled Carbon Monoxide (CO) — 2; 3 Participants
Diabetes Mellitus, Type 2
Primary: Time to the First Occurrence of Any of the Following Adjudication-confirmed Components of the Primary Composite Endpoint 3-point Major Adverse Cardiovascular (CV) Events…
Rotavirus
Primary: Percentage of Subjects With Anti-diphtheria (Anti-D) and Anti-tetanus (Anti-T) Antibody Concentrations Greater Than or Equal to (≥) the Cut-off Value — 100; 100; 98.6…
Rhinitis, Allergic, Perennial
Primary: Mean Weekly Total 4 Symptom Score (T4SS) During the Treatment Period — 2.89; 3.15 units on a scale — p==0.667
Colorectal Neoplasms
Primary: Association Between Neutrophil to Lymphocyte Ratio (NLR) [NLR ≤5 Versus NLR >5] and Progression-Free Survival (PFS) as Assessed by Hazard Ratio — 1.4 hazard ratio…