N/A N=106 Promoting Early Diagnosis of Congenital Hearing Loss With Patient Navigators
Congenital Hearing Loss
Primary: Number of Participants Who do Not Receive Diagnostic Audiological Testing (Aim 1) — 15; 8 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=1,098 Communities Helping the Hearing of Infants by Reaching Parents
Congenital Hearing Loss
Primary: Number of Participants Who do Not Receive Diagnostic Audiological Testing (Aim 1) — 378; 336 Participants
N/A N=129 Hearing Loss Prevention for Veterans
Hearing Loss, Noise-Induced
Primary: Percentage of Time Spent at Sound Levels >80 Decibels — 4.4; 5.0; 6.3 percentage of time — p=0.289
N/A N=55 A Pilot Study to Evaluate Patient Tolerance and Nursing Ease-of-Use of a Novel Hearing Protection Device
Hearing Impairment
Primary: Number of Participants With Skin Erythema After Device Application — 10; 10; 15; 14 Participants
Phase 2 N=188 Early Communication Intervention for Toddlers With Hearing Loss
Hearing Loss, Bilateral
Primary: Use of Communication Support Strategies - Parent — .60; .02 units on a scale
N/A N=236 Otoacoustic Emission Suppression Study
Neonatal Hearing Loss
Primary: Otoacoustic Suppression Measure — 1.95; 1.33; 2.48; 0.36 dB - Unitless Difference in dB SPL
Phase 2 N=72 Micronutrients to Prevent Noise-induced Hearing Loss
Noise-Induced Hearing Loss
Primary: Average Threshold Shift at 4 kHz in Both Ears — 3.94; 3.4; 2.77; 2.03 decibels — p=0.58
N/A N=20 Cochlear Implantation in Pediatric Cases of Unilateral Hearing Loss
Hearing Loss, Unilateral
Primary: Change Over Time in the Ability to Perceive Single Words as Assessed by Consonant-Nucleus-Consonant (CNC) Word Recognition Testing — 1.4; 14.4; 28.2; 45.0 percentage of…
Phase 4 N=25 Treating Hearing Loss to Improve Mood and Cognition in Older Adults
Hearing Loss · Depression
Primary: Hamilton Rating Score for Depression (HRSD) — 12.04; 13.86 score on a scale
N/A N=34 Longitudinal Outcomes of Hearing Aids
Presbycusis
Primary: Hearing Aid Benefit as Measured by the Glasgow Hearing Aid Benefit Profile (GHABP) — 3.68; 3.55; 3.63 score on a scale
N/A N=37 Use of Amplification in Children With Unilateral Hearing Loss
Unilateral Hearing Loss
Primary: HEAR-QL 26 Questionnaire — 69.61; 74.05; 71.04; 80.21 score on a scale
N/A N=38 Age-related Hearing Loss and Lexical Disorders
Alzheimer Disease · Presbycusis · Lexical Syntactic Disorder
Primary: Link Between Lack of Word and Presbycusis — 38; 38.5; 23; 21.5 score on a scale
Phase 3 N=131 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
Brain Tumor · Central Nervous System Tumor · Childhood Germ Cell Tumor
Primary: Incidence of Hearing Loss — 14; 31 Patients
N/A N=40 Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial
Hearing Loss
Primary: Change in Poor Ear Alone CNC Monosyllabic Word Understanding in Quiet — 0.09; 0.53; 0.44 percentage of words correct — p=<0.001
N/A N=28 Outcomes in Children With Pre-operative Residual Hearing
High Frequency Sensorineural Hearing Impairment · Hearing Disorders in Children
Primary: Mean CNC Word Scores — 71.0; 68.4 Percent Correct — p=.768
Phase 2 N=35 Valganciclovir Therapy in Infants and Children With Congenital CMV Infection and Hearing Loss
Cytomegalovirus Infection
Primary: Number of Ears That Had (1) Improved Hearing or no Change in Hearing (2) Worsened Hearing. — 27; 20; 1; 6 Ears — p=0.0859
N/A N=151 Baltimore HEARS: Hearing Health Equity Through Accessible Research & Solutions
Age-related Hearing Impairment 1 · Personal Communication
Primary: Change From Baseline in Hearing Handicap Inventory for the Elderly (HHIE-S) — -13.2; .06 score on a scale
Phase 2 N=53 Antioxidation Medication for Noise-induced Hearing Loss
Hearing Loss
Primary: Temporary Threshold Shift Measurement by Pure Tone Audiometry (A Total of Four Hearing Assessments Were Completed for Each Formulation Period on the 1st Day Pre- and…
N/A N=301 Vestibular Infants Screening-Flanders
Vestibular Disorder · Hearing Impaired Children
Primary: Number of Hearing-impaired Infants in Flanders With Abnormal Vestibular Screening Results. — 35 Participants
Phase 2 N=50 Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO)
Hypoxic-ischemic Encephalopathy · Neonatal Encephalopathy · Birth Asphyxia
Primary: Markers of Organ Function — 10; 6; 9; 12 participants
N/A N=18 Noise Reduction Preferences in Teenagers and Pre-teens
Hearing Loss
Primary: Subjective Rating of Listening Effort Questionnaire — 44.73; 44.5; 41.53; 35.86 units on a scale — p=0.007
N/A N=27 Audiobooks for Hearing Loss App as Auditory Training
Hearing Loss · Hearing Impaired Children · Hearing Impairment
Primary: Audiobooks Efficacy: Change in Slope of Curve for SNR Loss Scores on a Scale/Week for Partial BKB-SIN Hearing Test — 5.978; 5.889; 5.757; 5.600 units on a scale/week…
Phase 2 N=23 FX-322 in Sensorineural Hearing Loss
Sensorineural Hearing Loss
Primary: Number of Participants With Treatment-emergent Adverse Event(s) (TEAEs) — 2; 3; 5; 6 Participants
N/A N=133 Hearing Impairment, Strategies, and Outcomes in Emergency Departments
Hearing Loss · Emergency Service · Hospital Readmission
Primary: Number of Participants With Use of Hearing Assistance Device (HAD) During Emergency Department (ED) Stay — 38; 25 Participants
N/A N=24 Benefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss
Hearing Loss · Ear Diseases · Hearing Disorders
Primary: Change in Consonant Nucleus-Consonant (CNC) Word Recognition Test (Implanted Ear Only) — 2.13; 61.14 percentage of recognized words
N/A N=63 Prospective Research in Infants With Mild Encephalopathy
Hypoxic-Ischemic Encephalopathy · Brain Injury · Neonatal Seizure
Primary: Percentage of Infants With Evidence of Neurological Dysfunction, Brain Injury and/or Abnormality. — 28 Participants
N/A N=36 Optimizing Soft Speech Recognition in Children With Hearing Loss
Hearing Loss, Sensorineural · Hearing Loss, Bilateral
Primary: Speech Recognition in Quiet Using CNC (Consonant-Nucleus-Consonant) Word Lists — 6.06; 53.7; 66.61; 69.7 percentage of correctly repeated words — p=.005
Phase 4 N=52 Early Sodium Intake in Preterm Newborns
Hyponatremia · Premature
Primary: Hyponatremia — 6; 1 Participants — p=0.71
N/A N=11 Iowa Cochlear Implant Clinical Research Center Hybrid L24 and Standard Cochlear Implants in Profoundly Deaf Infants
Implants, Cochlear · Child · Hearing Loss, Bilateral
Primary: The Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS) — 0; 53; 64; 75 percentage out of 40
Phase 2 N=142 FX-322 in Adults With Acquired Sensorineural Hearing Loss
Hearing Loss, Sensorineural · Noise Induced Hearing Loss · Sudden Hearing Loss
Primary: Word Recognition in Quiet — 14.7; 11.1 Percent of subjects — p=0.525