Phase 3 N=251 Low Dose Aspirin for Venous Leg Ulcers
Venous Leg Ulcer
Primary: Time to Complete Healing of Reference Ulcer — 77; 69 days — p=0.246
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=144 Self-Management to Prevent Ulcers in Veterans With SCI (Spinal Cord Injury)
Pressure Ulcers · Spinal Cord Injuries
Primary: Percent of Possible Self-Reported Skin Care Behaviors — 73.8; 74.1; 83.5; 79.5 % of Possible Self-Reported Behaviors
Phase 2 N=29 The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot Study
Ulcer · Venous Ulcer · Skin Ulcer
Primary: Logarithm of Percentage of Baseline Ulcer Size — 3.6043; 3.5030 Mean of log (percentage of baseline area — p=0.652
Phase 2 N=228 Dose Finding Study of HP802-247 in Venous Leg Ulcers
Venous Leg Ulcer · Venous Stasis Ulcers
Primary: The Average Percent (%) Change From Baseline in the Target Wound Area in Each Treatment Group Over the Twelve-week Double-blind Treatment Period. — -77.11; -70.15…
Phase 2 N=140 Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence
Venous Hypertension Ulcers · Venous Stasis Ulcer · Venous Ulcer
Primary: Number of Participants With Ulcer Recurrence — 6; 3; 11; 5 participants — p=0.091
N/A N=12 A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers.
Diabetic Foot Ulcer · Peripheral Arterial Disease · Wound; Foot
Primary: Transcutaneous Oxygen Pressure (TcPO2) — 50.96 mmHg
N/A N=81 Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg Ulcers
Venous Insufficiency · Venous Reflux · Lower Extremity Ulcer
Primary: Wound Area Mean Percent Reduction — 45.8; 61.6 percentage of mean area reduction — p=<0.024
Phase 2 N=175 Preventing Diabetic Foot Ulcers Through Cleaner Feet
Diabetic Foot Ulcer
Primary: Time to New Foot Complication Among All Randomized Participants — 12; 14 Participants
Phase 2 N=80 Herbal Preparation Used as Adjuvant Therapy on Diabetic Ulcers
Diabetic Foot Ulcer · Amputation
Primary: Number of Participants With Limb Salvage — 37; 31 Participants
N/A N=8 ULCERS - Electrical Stimulation in Diabetic Foot Ulceration
Diabetes
Primary: Number of Day Until 50% Healing of Leg Ulcer — 55; 30 Days
Phase 3 N=155 Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers >12 cm2 to ≤ 36 cm2
Venous Leg Ulcers
Primary: Wound Closure — 17; 23 participants
Phase 2 N=121 Dose-response Relationship Study of S42909 on Leg Ulcer Healing
Venous Leg Ulcer
Primary: Relative Reduction of Reference Ulcer Area After 4 Weeks of Treatment on Top of Standard of Care Compared With Baseline Reference Ulcer Area (W000) Assessed During Study…
N/A N=47 MIST Ultrasound Therapy Compared to United Kingdom Standard Care for the Treatment of Non-healing Venous Leg Ulcers
Varicose Ulcer
Primary: Percentage Change in Wound Area — -39.2; -46.6 percentage change in wound area — p=0.565
N/A N=90 Blu Light for Ulcers Reduction
Leg Ulcers Venous · Dehiscence, Surgical Wound
Primary: Size of Wound Remaining Compared to Initial Wound Size — 42.58; 53.78 percentage of the remaining area
Phase 3 N=447 Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers
Venous Leg Ulcers
Primary: Compare the Treatment Groups for the Proportion of Subjects With Complete Wound Closure Over the 12-Week Treatment Period From Baseline — 129; 126; 82; 84 participants…
Phase 3 N=68 Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Biopsies — 2.46; 2.64; 2.56; 2.07 UI/dL
Phase 4 N=201 Evaluating the Efficacy of an Absorbent Foam Dressing Containing Silver (Mepilex Ag) Versus the Same Dressing Without Silver Used on Subjects With Venous Leg Ulcers or Mixed Ulcers
Venous Leg Ulcers · Mixed Leg Ulcers
Primary: Efficacy Will be Defined as Absolute Wound Size Reduction. — -4.65; -5.09 cm2
N/A N=11 Healing Rate of Leg Wounds Treated With Contact and Noncontact Ultrasound: The VIP Ultrasound Protocol
Chronic Ulcer of Lower Extremity
Primary: Total Wound Area — 7.93125; 7.93125; 1.3275; 8.80875 Squared centimiters
N/A N=83 Leg Ulcers Standards of Care Enhancement
Venous Leg Ulcer · Mixed Leg Ulcer
Primary: Percentage Change of the Wound Area — 42.41; 60.75; 25.18; 72.16 percentage of change
Phase 2 N=23 Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers
Skin Ulcers · Sickle Cell Anemia
Primary: Healing Defined as a Decrease in Ulcer Area by at Least 25% of the Initial Area — 24; 78 percentage of healed ulcers — p=0.05
Phase 4 N=40 Ulcer Prevention Study in Post Gastric Bypass Patients
Marginal Ulcers
Primary: Number of Participants With Complaints, Specifically About Pain, Vomiting, Dyspepsia, and/or Dysphagia. — 17; 13 participants
Phase 3 N=537 Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers
Venous Leg Ulcer
Primary: Complete Healing of the Study Ulcer by Week 16. — 201; 176 participants — p=0.1030
N/A N=31 VLU Dressing Study
Venous Leg Ulcer
Primary: Change in Bacterial Load — 12678.81; 33190.8 CFU/gram
N/A N=28 Predictive of Biomarkers of Healing in Chronic Venous Ulceration of the Lower Limb
Varicose Ulcer
Primary: Identification of Biomarkers Predictive of Ulcer Healing. — 9 Number of biomarkers
N/A N=52 Effect of Intermittent Pneumatic Compression on Ulcer Healing in Subjects With Secondary Lymphedema
Lymphedema
Primary: Median Time to Wound Closure at 9 Months — 141; 211 median number of days for complete heali
N/A N=450 Early Venous Reflux Ablation Ulcer Trial
Venous Leg Ulcer
Primary: Time to Ulcer Healing From Date of Randomisation to Date of Healing up to 365 Days — 82; 56 days
Phase 4 N=106 DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes
Chronic Foot Ulcers
Primary: Full Epithelialization of the Wound — 16; 8 participants — p=<0.05
Phase 2 N=40 Evaluation of Safety and Activity of Celaderm in Healing Venous Leg Ulcers
Leg Ulcer · Varicose Ulcer
Primary: Primary Efficacy: Cumulative Proportion of Patients Completely Healed by the End of the Treatment Period, as Judged by the Investigator's Direct Observation. — 1; 4; 3…
Phase 2 N=90 Compression Device Versus 4-layer Compression System
Leg Ulcers
Primary: Safety Measured by the Number of Subjects With Adverse Events (Including Any Deterioration of Ulcer) — 33; 47 Number of Subjects with Adverse Events
N/A N=31 Diabetic Foot Ulcer Study on Topical Interventions
Diabetic Foot
Primary: Number of Participants With Complete Healing of Ulcer During the Observation Period — 9; 5; 4 participants