Phase 4 N=38 Liraglutide Effects on Epicardial Fat Inflammatory Genes
Type2 Diabetes · Coronary Artery Disease
Primary: EAT Inflammation — 0.70; 1.4; 0.39; 0.25 ct (cycle threshold)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=58 Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW)
Epilepsies, Partial
Primary: Treatment Failure — 11; 11 Participants
Phase 4 N=74 The HOME Study (HPN With OMEGA-3)
Patients Requiring Home Parenteral Nutrition
Primary: Change of Liver Function Parameters From Baseline to Visit 2 — 0.0606; -0.0703 normalized sum- no unit — p=0.025
Phase 4 N=33 Effects of NOV03 on the Tear Film
Dry Eye Disease (DED)
Primary: Thickness of the Mucus-aqueous Tear Film Layer — 3920.3 nm
Phase 4 N=100 DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men
Adherence, Medication · Risk Behavior · Pre-Exposure Prophylaxis
Primary: Effect of DOT Diary App on PrEP Adherence — 39; 19 Participants — p=0.94
Phase 4 N=267 Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI
Acute Kidney Injury
Primary: Renal Function — .46; .75; 4.26; 2.80 mL/min/1.73m^2 — p=>0.05
Phase 4 N=147 Doravirine for Obese Persons on Integrase Inhibitors and Tenofovir Alafenamide
HIV Infections
Primary: Mean Change (Percent) in Body Weight (kg) From Entry to Week 48 — -0.47; -2.73; -1.84 relative change % — p=0.23
Phase 4 N=27 Reducing the Risk of Drug-Induced QT Interval Lengthening in Women
Long QT Syndrome · Abnormalities, Drug-Induced
Primary: Baseline (Pre-ibutilide) QT-F Intervals — 417; 421; 413; 414 ms — p=0.07
Phase 4 N=100 Study of the Efficacy and Safety of Pegnano Plus Barivir (Ribavirin) in Treatment-naïve Patients With Chronic Hepatitis C at KienGiang General Hospital
Chronic Hepatitis C
Primary: Sustained Virological Response (SVR) — 17; 10; 56; 83 Participants — p=0.008
Phase 4 N=214 Efficacy of IV Acetaminophen Versus Oral Acetaminophen
Nephrectomy
Primary: Total Opioid Dose (MME) Used in 24 Hours — 103.61; 109.17 total morphine milligram equivalents — p=0.3938
Phase 4 N=60 Does The Addition Of Divalproex Sodium ER To An Atypical Antipsychotic Drug (APD) Improve Cognition And Psychopathology In Outpatients With Schizophrenia (SCH) Or Schizoaffective Disorder (SAD)?
Schizophrenia · Schizoaffective Disorder
Primary: Change in Cognition and Psychopathology Disorders as Measured on the MATRICS Consensus Cognitive Battery (MCCB) — 14.1; 14.3 units on a scale
Phase 4 N=103 Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures
Eyelid Tumor · Eyelid Bump · Eyelid Deformity
Primary: Pain on Injection — 2.8; 3.6 score on a scale
Phase 4 N=72 Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
Covid19 · Sequelae of; Infection · Cognitive Symptom
Primary: Effect of Niagen on NAD+ and Cognitive Functioning — -0.104; -0.214; -0.014; -0.147 units on a scale
Phase 4 N=500 Ultra Curto (Ultra Short) TB Prevention Therapy
Tuberculosis
Primary: Number of Participants Who Complete Treatment With >90% Adherence — 223; 211 Participants — p=0.07
Phase 4 N=110 COBRA-Slim With or Without Fast Access to TNF Blockade for Remission Induction in Early RA
Arthritis, Rheumatoid
Primary: Area Under Curve (AUC) of Disease Activity Score Based on a 28 Jointcount and C-reactive Protein (DAS28CRP) — 297.4; 300.7 units on a scale*week — p=<0.05