Phase 1 N=61 OxyNorm® Capsules (Immediate-Release) Pharmacokinetic (PK) Study
Pain
Primary: AUC0-t and AUC0-∞ for Participants Who Received a Single Dose — 57.03; 102.10; 205.89; 58.38 ng*hr*ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=88 Beta Cell Restoration Through Fat Mitigation
Prediabetes · Type 2 Diabetes · Obesity
Primary: Steady State Beta Cell Compensation — 3.01; 3.19 (nmol/L) adjusted for M/I — p=0.05
N/A N=138 Meningococcal Quadrivalent CRM-197 Conjugate Vaccine Infant Study
Meningococcal Disease · Infections, Meningococcal
Primary: Number of Subjects Who Experienced Single or Multiple Medical Encounters — 16; 24 Participants
Phase 3 N=151 Study of BEMA™ Fentanyl in the Treatment of Breakthrough Pain in Cancer Subjects
Pain · Cancer
Primary: Summary of Pain Intensity Differences (SPID) — 47.9; 38.1 Score on a scale — p=0.004
N/A N=98 Clinical Follow-up and Outcomes of Pregnancies Exposed to Ella
Emergency Contraception
Primary: Number of Participants Who Experienced Assessed Pregnancy Outcomes — 1; 0; 1; 0 Participants
Phase 4 N=30 Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant
Renal Transplant Rejection · Immunosuppression
Primary: Cytokines Evaluation — 380; 893; 763; 147 MFI — p=<0.05
N/A N=148 Concept Mapping as a Scalable Method for Identifying Patient-Important Outcomes
Concept Mapping Versus Interviews
Primary: Comprehensiveness of Interviews as Compared to One Concept Mapping Group — 26; 33; 6; 13 Reported patient-important outcomes
N/A N=13 Tx for Child Sexual Behavior Problems
Sexual Behavior
Primary: Child Sexual Behavior on the Child Sexual Behavior Inventory (CSBI) — 28.8; 18.1 Scores on a scale
N/A N=150 Improving Child Restraint Installation
Car Seat Installation
Primary: Number of Participants Who Accurately Select a Safe Child Restraint — 131; 121 Participants — p=<.001
N/A N=51 Skin Camouflage for Women Prisoners With Self-Harm Scarring
Self Injurious Behaviour
Primary: Warwick-Edinburgh Mental Well-being Scale — 40.1739; 30.8182 score on a scale
N/A N=400 Cryotherapy vs. LEEP to Treat Cervical Intraepithelial Neoplasia (CIN) 2/3 Among HIV-positive Women
Cervical Intraepithelial Neoplasia
Primary: Recurrence of Cervical Intraepithelial Neoplasia Among HIV-positive Women — 60; 37 Participants
Phase 2 N=180 Dose Ranging Study of ALX-0171 in Infants Hospitalized for Respiratory Syncytial Virus Lower Respiratory Tract Infection
Respiratory Syncytial Virus Lower Respiratory Tract Infection
Primary: Time for Viral Load to Drop Below Assay Quantification Limit (BQL) (Plaque Assay Analysis) — 46.1; 14.2; 5.1; 5.1 hours — p=<0.001
Phase 4 N=239 A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip and Knee Arthroplasty
Total Hip and Knee Arthroplasty
Primary: Pain Score — 3.78; 3.85; 3.3; 3.4 score on a scale
N/A N=376 Patient Activation to Address Chronic Pain and Opioid Management in Primary Care
Chronic Pain
Primary: Patient Activation — 65.8; 65.2; 67.3; 67.7 units on a scale
N/A N=105 Ultra Low Dose CT for CACS and AC of SPECT
Coronary Artery Disease
Primary: Agreement and Correlation of Coronary Artery Calcium Score Obtained From Ultra-low-dose and Standard CT — 212; 178 Agatston score