Phase 4 N=340 The Efficacy of Claritin in Healthy Subjects
Healthy
Primary: Change in Wheal Reaction Area From Baseline --- 2 Hour — 27.5; 29.0; 30.97; 25.0 Percent change
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=157 Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continuation, and Depression
Contraception · Postpartum Depression · Lactation
Primary: Duration of Breastfeeding Among Women Who Plan to Breastfeed Their Infants After Postpartum or Delayed (4-6 Weeks Postpartum) Initiation of DMPA — 71; 70; 4; 4…
Phase 4 N=255 Japanese Treat and Extend Study of Aflibercept in Neovascular Age-related Macular Degeneration
Wet Macular Degeneration
Primary: Mean Change From Baseline in BCVA at Week 52 — 9.0; 8.4 letters
Phase 4 N=18 Rejuvenation of the Lower Eyelid Using a Combination of Two Hyaluronic Acid Fillers - a Pilot Study
Infraorbital Hollows
Primary: The Primary Objective of This Study is to Determine the Efficacy and Longevity of the Use of Restylane® and Perlane® in Combination for the Rejuvenation of the…
Phase 4 N=97 The Effectiveness And Safety Of Donepezil Hydrochloride (E2020) In Subjects With Mild To Severe Alzheimer's Disease Residing In An Assisted Living Facility
Mild to Severe Alzheimer's Disease
Primary: Mini Mental State Examination (MMSE) Total Scores by Visit — 18.7; 20.8; 20.5; 20.5 Scores on a scale
Phase 4 N=109 Administration of Pre-Operative Gabapentin to Patients Undergoing Laparoscopy
Postoperative Pain
Primary: NRS (Numerical Rating Scale) — 3.5; 3.4; 5.4; 5.5 units on a scale — p=0.89
Phase 4 N=41 Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
Obstetric Pain
Primary: Maternal Cytokine IL-10 Levels of pg/ml Upon Enrollment — 12.7; 14.2 pg/ml
Phase 4 N=221 Results Of Patient Rated Asthma Control Test In Comparison To Diary Card Data
Asthma
Primary: Percentage of Well Controlled Participants as Per Gaining Optimal Asthma Control (GOAL) Criteria After 12 Week Compared to Percentage of Participants With Asthma Control…
Phase 4 N=8 Pharmacogenetics to Predict Drug Interactions in Kidney Transplant Recipients
Kidney Transplantation
Primary: Tacrolimus Bioavailability (F) — 0.224; 0.681 ratio of oral to IV — p=0.006
Phase 4 N=230 Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness
Opioid-Induced Constipation
Primary: The Proportion of Subjects Who Have a Rescue-free Laxation Response Within 4 Hours After at Least 2 of the First 4 Doses — 62.9; 9.6 percentage of participants — p=<…
Phase 4 N=149 Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness
Opioid-Induced Constipation
Primary: Number of Laxations Per Subject Within 24 Hours of Dosing Per Week. — 1.7; 2.4; 2.6; 3.4 Number of laxations
Phase 4 N=114 Trial Liposomal Bupivacaine Following Retropubic Suburethral Sling for Stress Urinary Incontinence
Urinary Incontinence, Stress
Primary: Pain in the Morning — 9.5; 27.0 scores on a scale — p=0.014
Phase 4 N=8 Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal Hypercortisolism
Mild Hypercortisolism
Primary: A1C Level — 6.2; 6.1375; 6.125 percentage of red blood cells
Phase 4 N=620 MENOPUR® in a Gonadotropin-Releasing Hormone (GnRH) Antagonist Cycle With Single-Blastocyst Transfer in a High Responder Subject Population
Infertility
Primary: Ongoing Pregnancy Rate — 35.5; 30.7 percentage of participants
Phase 4 N=206 Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and Overweight
Depression
Primary: Change of Beck Depression Inventory-II Scores Over 16 Weeks — 18.82; 17.50; 22.68; 22.03 units on a scale — p=<0.05