17,261 trials
Presbyopia
Primary: Percent of Subjects With ≥ 15 Letters of Improvement in Photopic Binocular DCNVA — 60.5; 30.0; 45.2; 27.3 percentage of subjects with ≥ 15 letters
Immunoglobulin A Nephropathy
Primary: Change in Slope of First Morning Urinary PCR From the 8-week RAAS Blocker run-in Period to the 12-week CCX168 Treatment Period — -2.4; 15.3; -23.9 mg/g/week — p=0.965
Acute Myeloid Leukemia · Chronic Myelogenous Leukemia, BCR-ABL1 Positive · Cord Blood Transplant Recipient
Primary: Number of Participants With Dose Limiting Toxicities — 0 Participants
Moderate-to-severe Atopic Dermatitis
Primary: Percent Reduction in EASI Score From Baseline to Week 16 — 57.56; 63.03; 63.50; 39.67 percent reduction from Baseline — p=0.0007
Brain Metastases
Primary: Sensitivity of 18F Fluciclovine PET for Detecting Recurrent Brain Metastases at Different Visual Thresholds — 100; 100; 100; 100 percentage of participants
Trichotillomania (Hair-Pulling Disorder) · Dermatillomania
Primary: NIMH Symptom Severity Scale (for TTM or Skin Picking) — -1.19; -6.98 units on a scale
Vestibular Schwannoma
Primary: Surgeon Predicted Use of Fluorescein Sodium in Future Cases — 0; 0; 4; 3 participants
Type 2 Diabetes
Primary: Change in Absolute Gluconeogenesis From Baseline to 12 Weeks — 0.018; -0.050 mg/kg LBM/min
Fibromyalgia
Primary: Revised Fibromyalgia Impact Questionnaire (FIQ-R) Total Score — -8.7; -3.0 score on a scale
Coronary Artery Disease (CAD) · Ischemic Heart Disease
Primary: Intra-reader Difference of Summed Rest Score (SRS) for Positron Emission Tomography (PET) Myocardial Perfusion Imaging (MPI) — 6.662; 6.513; 6.235; 6.219 score on a…
Heart Failure
Primary: Win Ratio of Composite Endpoint — 228; 206 Number of Wins for the group
Breast Cancer
Primary: Change in the Rate of Adverse Cosmesis (Defined as Fair or Poor Cosmesis) Compared to Baseline Using the Harvard Cosmetic Rating: — 2; 0; 0 Participants
Acute Biphenotypic Leukemia · Acute Lymphoblastic Leukemia · Acute Myeloid Leukemia
Primary: Number of Participants With Relapsed Leukemia — 3; 5 Participants
Uncontrolled Hypertension
Primary: Change From Baseline in Mean Seated Systolic BP (SBP) — -16.6; -17.0; -16.0; -19.8 mmHg
Covid19 · Coronavirus Infection
Primary: World Health Organization (WHO) Ordinal Scale Score — 26; 22; 1; 2 Participants