65,437 trials
Muscle Invasive Bladder Cancer · High Risk Urothelial Carcinoma of the Upper Urinary Tracts
Primary: Percentage of Participants With Complete Response at Cystectomy or Ureterectomy Following Preoperative Dose Dense MVAC — 38 percentage of total participants
No Disease State or Condition
Primary: Stage II: Duration of Anesthesia as Measured by Pin Prick Test (PPT) for One Spray CTY-5339-A Compared to One Spray CTY-5339-CB — 14.6; 7.4 minutes
Cystic Fibrosis
Primary: Absolute Change in Total Brody/CF-CT Score — 0.90; 2.38 scores on a scale
Rheumatoid Arthritis
Primary: Number and Percentage of Subjects With American College of Rheumatology 20 (ACR20) at Week 12 — 45; 48; 51; 50 Participants
Osteoarthritis (OA)
Primary: Safety - Number of Participants With Treatment-Emergent Serious Adverse Events — 0; 0; 0; 0 Participants
Healthy
Primary: Biphasic Alcohol Effects Scale - Stimulation — 11.3; 3.9; 8.7; 3.2 units on a scale
Pediatrics · Muscle Spasticity · Cerebral Palsy
Primary: Percentage of Participants With at Least One Treatment- Emergent Adverse Event (TEAE) — 58.7 percentage of participants
Patient-centered Medical Home Implementation
Primary: WH-PACT Achievement — 30; 23; 49; 20 Participants — p=0.637
Rheumatoid Arthritis
Primary: Number and Percentage of Subjects Achieving American College of Rheumatology (ACR) 20 Response at Week 12 — 52; 57; 53; 50 Participants — p=0.172
Depression · Sexual Dysfunction
Primary: Change in Massachusetts General Hospital Sexual Dysfunction Inventory Scores — .249; .017 score on a scale — p=.016
Smoking
Primary: Levels of High Density Lipoprotein C (HDL-C). — 54.1; 50.9; 56.3; 52.8 mg/dL — p=<0.001
Neonatal Seizures
Primary: Neonates With Seizure Cessation When Given Levetiracetam (40-60 mg/kg) as First Line Therapy Compared to Phenobarbital (20-40mg/kg) — 15; 24 Participants — p=<0.001
Sclerosing Cholangitis
Primary: Adverse Event Frequency — 8 Participants
Nonalcoholic Fatty Liver Disease · HIV
Primary: Efficacy of Aramchol 600 mg vs. Placebo in Improving Hepatic Steatosis Assessed by Magnetic Resonance Imaging in Patients With HIV-associated NAFLD — 13.7; 11.1…
Bradycardia
Primary: Freedom From MRI Scan-related Complications — 123 Participants — p=<0.01