Phase 4 N=29 Trial of Carvedilol in Alzheimer's Disease
Alzheimer's Disease
Primary: Hopkins Verbal Learning Test (HVLT) Scores at Baseline, 3, and 6 Months — 13; 12; 12; 13 Scores on a scale — p=0.565
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=8 rtPA in in the Prevention of CVAD-Associated Thrombosis and Infection in Pediatric Patients With Short Bowel Syndrome
Short Bowel Syndrome
Primary: Development of CVAD Line Thrombosis — 0 thromboses
Phase 4 N=32 Effects of Dapagliflozin 10 mg on Insulin Resistance in Patients With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus
Primary: Adjusted Change From Baseline in Skeletal Muscle Insulin-stimulated Gluocose Uptake — 0.28; 0.28 umol/min/kg — p=0.9984
Phase 4 N=285 Dexmedetomidine and Delirium in Patients After Cardiac Surgery
Delirium · C.Surgical Procedure; Cardiac · Postoperative Complications
Primary: Incidence of Postoperative Delirium — 7; 11 Participants — p=0.341
Phase 4 N=18 Non-Pharmaceutical Treatment of Seasonal Allergic Conjunctivitis
Hypersensitivity
Primary: Symptoms — 15.3; 11.3; 13.3; 9.8 Units on a scale
Phase 4 N=399 Colchicine Or Naproxen Treatment for ACute gouT
Gout
Primary: Change in Pain Intensity — 3.5; 3.8 units on a scale
Phase 4 N=936 Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine
Rhinitis, Allergic, Seasonal
Primary: Mean Change From Baseline Over the Two-week Treatment Period in Nighttime Symptoms Score (NSS) — -1.9; -2.9; -2.0; -0.6 Scores on a scale — p=<0.001
Phase 4 N=42 A Pharmacokinetic Study Comparing VI-0521 With Placebo in Obese Adolescents
Pediatric Obesity · Childhood Obesity
Primary: Apparent Clearance (CL/F) of Phentermine and Topiramate — 7.33; 7.04; 7.33; 7.18 L/h
Phase 4 N=597 Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft Angioplasty
Saphenous Vein Graft Atherosclerosis
Primary: Number of Participants With Target Vessel Failure (TVF), Defined as the Composite of Cardiac Death — 16; 17 Participants
Phase 4 N=145 Omalizumab to Mepolizumab Switch Study in Severe Eosinophilic Asthma Patients
Asthma
Primary: Mean Change From Baseline in Asthma Control Questionnaire-5 (ACQ-5) Score at Week 32 — -1.45 Scores on a scale — p=<0.001
Phase 4 N=93 The Impact of Grass SLIT Treatment on Birch Pollen Induced Allergic Rhinitis - a Pilot Evaluation
Allergic Rhinoconjunctivitis
Primary: Change in Total Nasal Symptom Score (TNSS) From Baseline to Post-treatment. — 2.3; 2.2 Scores on a scale
Phase 4 N=894 Long-Acting Reversible Contraception
Contraception
Primary: Contraceptive Method Discontinuation — 300; 62; 142 Participants
Phase 4 N=130 Citicoline for Bipolar 1 Disorder and Cocaine Dependence
Bipolar Disorder · Cocaine Dependence
Primary: Percentage of Participants With Presence of a Cocaine-Positive Urine Screen — 59.0; 49.2 percentage of participants
Phase 4 N=146 A Study of Anagrelide and Hydroxyurea in High-Risk Essential Thrombocythemia Patients
Thrombocythemia, Hemorrhagic
Primary: Change From Baseline in Left Ventricular Ejection Fraction (LVEF) Over Time — 66.4; 66.9; 0.5; -1.1 percentage of ejection fraction
Phase 4 N=36 Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM
Disorder of Glucose Regulation
Primary: Normalization of Glucose Levels — 9; 2; 4 Participants — p=.035