Phase 2 N=11 Continuation Study of the Oral AKT Inhibitor GSK2110183
Cancer
Primary: Number of Participants With at Least One Adverse Events (AEs) — 11 Participants
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=6 Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access
Stroke · Intracranial Hypotension · Cerebral Edema
Primary: Number of Subjects With Tissue Damage — 0 Participants
N/A N=28 Growth Hormone Feedback to Insulin-like Growth Factor-I (IGF-1) and Oral Glucose Tolerance Test (OGTT)
Acromegaly · Type 2 Diabetes Mellitus
Primary: Percentage With Growth Hormone (GH) Suppression to < 0.4 ng/ml — 0; 7; 8 Participants
Phase 3 N=1,102 Study of Secukinumab Compared to Ustekinumab in Subjects With Plaque Psoriasis
Plaque Psoriasis
Primary: Participants Who Achieved Psoriasis Area and Severity Index (PASI) 90 Response at Week 12 — 366; 265 Participants — p=<0.0001
Phase 4 N=91 Study to Evaluate the Effect of Secukinumab Compared to Placebo on Aortic Vascular Inflammation in Subjects With Moderate to Severe Plaque Psoriasis
Chronic Plaque Psoriasis
Primary: Aortic Vascular Inflammation as Measured by FDG-PET/CT — 1.6615; 1.6333; 0.0143; 0.0655 target to background ratio (TBR) — p=0.3712
N/A N=34 Sugar Champ: Pilot Social Network Intervention to Reduce Intake of Sugary Drinks
Overweight and Obesity
Primary: Number of Sessions Attended — 9 Number of sessions
Phase 3 N=250 A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis
Bacterial Vaginosis
Primary: Number of Women With Clinical Cure at the End of Treatment Visit (EOT) — 59; 19 Participants — p=<0.001
Phase 3 N=18 Dyanavel® XR Extended-Release Oral Suspension in the Treatment of Children With ADHD: A Laboratory School Study
Attention Deficit Hyperactivity Disorder
Primary: Change in Swanson, Kotkin, Agler, M-Flynn, and Pelham (SKAMP) Combined Scores, Baseline to 30 Minutes Post Dose — -6.1; 2.5 number of questions answered correctly…
N/A N=83 Repetitive Position Change Improves Gastric Cleanliness for MCE
Stomach Diseases
Primary: Image Cleanliness of Gastric Cavity — 3.0; 3.5; 2.2; 3.0 units on a scale
Phase 4 N=85 Negative Beta Glucan in ICU Patients
Candidemia
Primary: Evaluate the Ocurrence of Candidemia in Patients With Negative 1,3 Beta-D-glucan Who Discontinue Anidulafungin — 0; 21 Participants
Phase 1 N=58 Phase 1 Study of ACE-083 in Healthy Subjects
Musculoskeletal Diseases
Primary: ACE-083 Safety and Tolerability: Number of Subjects With Adverse Events — 6; 6; 6; 6 Participants
N/A N=1,313 Patient Convenience Study- NIS RELATE
Atrial Fibrillation
Primary: Mean Perception of Anticoagulant Treatment Questionnaire, Part 2 (PACT-Q2) Scores, for Patients in Cohort A, at Second Assessment Compared to Baseline Assessment — 71.4…
N/A N=12 Study to Investigate the Long Term Survivorship of Coflex
Spinal Fractures
Primary: Number of Participants With Radiographic Analysis of Evidence of Fracture or Healing Based on CT Scan — 8 Participants
Phase 2 N=200 Efficacy of Enteral Iron Supplementation in Critical Illness
Anemic, Critically Ill Patients
Primary: Hematocrit — 29.3; 29.1; 28.6; 28.2 percentage of RBC in blood
N/A N=35 The Consumption of Beef on Appetite and Cognitive Function
Obesity · Poor Glycemic Control · Dietary Interventions
Primary: Daily Energy Intake: Total Daily Intake — 2859; 2313; 2714; 2396 kcal