17,261 trials
Desmoid Tumor
Primary: Immunohistochemical Immunoreactive Score Results After 4 Weeks of Sirolimus Compared to Control Specimens — 5.22; 7.44; 4.47; 9.39 score on a scale — p=0.63
Solid Tumor
Primary: Number of Participants With Adverse Events (AEs). — 8; 6; 12; 7 Participants
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Primary: Percentage of Participants Who Achieved Adequate Control of Intravascular Hemolysis — 75.0 Percentage of Participants
Depressive Disorder, Major
Primary: Change From Treatment Baseline in Montgomery Asberg Depression Rating Scale (MADRS) Total Score at Treatment Week 6 in Participants Who Were Non-Responders During…
Autoimmune Pulmonary Alveolar Proteinosis
Primary: Time to Rescue WLL — 18; 30 Months — p=0.0078
Extensive Stage Lung Small Cell Carcinoma · Recurrent Lung Small Cell Carcinoma
Primary: Progression-free Survival (PFS) — 5.5; 4.9 months — p=0.17
Marginal Zone Lymphoma · Waldenstrom Macroglobulinemia · Non Follicular Indolent Non-Hodgkin Lymphoma
Primary: Overall Response Rate (ORR) as Assessed by Revised Response Criteria for Non- Hodgkin's Lymphoma (Lugano Classification) and Consensus-Based 6th International Workshop…
Postoperative Gastrointestinal Dysfunction
Primary: Time From End of the Surgery to Resolution of Upper and Lower Gastrointestinal (GI) Function Postsurgery as Assessed by the Investigator — 1.89; 2.76; 2.59; 2.62 days…
Respiratory Syncytial Viruses · Respiratory Tract Infections
Primary: Number of Participants With Solicited Local Adverse Events (AEs) for 7 Days After First Vaccination — 8; 1; 14; 4 Participants
COVID-19 · Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Primary: Oxygen Index (OI) — -0.91 index
EoE · Eosinophilic Esophagitis
Primary: Mean Change in Dysphagia Score — 15.4; 8.3 score on a scale — p=0.14
Ebola Virus Disease
Primary: Main Study: Percentage of Participants With Solicited Local and Systemic Adverse Events (AEs) up to 7 Days Post-dose 1 — 14.7; 6.1; 36.0; 30.3 Percentage of Participants
Healthy
Primary: Change in Anti- A/H1N1 Antibody Titer — 65.0; 73.2; 88.4; 20.3 titer
Alcohol Drinking · Control
Primary: Quantifying the Difference in Glutamate Levels (mmol/kg) During N-Acetylcysteine Versus Placebo in the Anterior Cingulate Brain Region. — 15.7527667; 15.6265229 mmol/kg…
Healthy
Primary: Adults of Groups 1, 2 and 3: Percentage of Participants With Serological Response to Vaccination as Measured by Virus Neutralization Assay (VNA) Titers at 28 Days After…