Phase 3 N=800 Study of TAS-102 in Patients With Metastatic Colorectal Cancer Refractory to Standard Chemotherapies
Colorectal Cancer
Primary: Overall Survival — 7.1; 5.3 months — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=52 Milk in Life Conditions (MiLC): Bacterial Composition of Human Milk Pumped and Stored in "Real-Life" Conditions
Human Milk Microbiome · Bacterial Growth
Primary: Bacterial Community Richness — 64.2; 58.9; 64.0; 60.8 Observed taxa — p=0.9
N/A N=142 Massive Iron Deposit Assessment
Iron Overload · Excessive Body Iron Burden
Primary: Hepatic Iron Content in the Liver Using Liver Biopsy — 19.8 mcg
Phase 2 N=55 Detection of High Grade Prostate Cancer With Subharmonic Ultrasound Imaging, A Pilot Study
Prostatic Neoplasm
Primary: Percentage of Subjects Whose Prostate Cancer Was Detected With Subharmonic Imaging — 24 Participants
N/A N=30 A Pilot Clinical Study to Evaluate the Safety and Efficacy of Marketed Oxalate Strips Compared to a Marketed Safety Pen
Dentin Sensitivity
Primary: Change From Baseline Visual Analog Scale — -22.933; -3.200 Units on a scale
Phase 3 N=644 Phase 3 Efficacy and Safety Study of Peginterferon Lambda-1a and Ribavirin With Telaprevir
Hepatitis C Virus
Primary: Percentage of Participants With Extended Rapid Virologic Response (eRVR) - Part A — 51.9 Percentage of participants
N/A N=15 A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline Cold Water Challenge — -1.00 Units on a scale
Phase 2 N=40 Gulf War Illness Nasal Irrigation Study
Persian Gulf Syndrome · Chronic Sinusitis · Fatigue
Primary: Change in Sino-Nasal Outcome Test (SNOT-20) Score From Baseline — -16.9; -8.8; -3.4; -18.9 score on a scale
Phase 2 N=125 Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain
Melanoma and Brain Metastases
Primary: Intracranial Response (IR) Rate in Cohort A — 45 Number of participants — p=<.0001
Phase 3 N=299 Efficacy and Safety Evaluating Study to Compare Uritos® (Imidafenacin) and Urotol® (Tolterodine) for Treatment of Overactive Bladder.
Overactive Bladder
Primary: Change in the Mean Daily Number of Urination Episodes at Week 12 — 12.5; 11.9; 9.0; 8.6 urination episodes per day — p==0.5595
Phase 4 N=37 Tamoxifen to Reduce Unscheduled Bleeding in New Users of the Levonorgestrel-releasing Intrauterine System (LNG-IUS)
Menorrhagia · Metrorrhagia · Medicated Intrauterine Devices
Primary: Number of Bleeding and Spotting Days — 16.8; 12.0 days
Phase 2 N=66 Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia · Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
Primary: Disease Free Survival Defined From the Date of First Induction Complete Response (CR) to Relapse or Death Due to Any Cause — 52.6 percentage of patients
Phase 4 N=70 Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy
Femoracetabular Impingement · Pain, Postoperative
Primary: Opioid Consumption in the Acute Postoperative Period — 57.3; 56.0; 37.0; 40.1 milligram morphine equivalents (mEq)
Phase 4 N=14 The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major Depression
Depression
Primary: Response to Medications as Assessed by Change in Score on Modified MDRS Scale From Baseline to End of Study Period — 3.5; 12.5 units on a scale — p=0.03
N/A N=16 AF Septal Pacing (Clinical Investigation Plan)
Paroxysmal Atrial Fibrillation · Persistent Atrial Fibrillation
Primary: Number of Electrodes in a Stable Position — 38 Electrode pairs