65,437 trials
Acromegaly
Primary: Acromegaly Quality of Life (ACROQoL) Global Score — 57; 60; 54 points on a scale
Arteriovenous Malformations
Primary: Number of Participants With Catheter-related Adverse Events at 30 Days — 0 Participants
Treatment-resistant Depression
Primary: Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) — 90.1 Percentage of participants
Attention Deficit Hyperactivity Disorder (ADHD)
Primary: ADHD-IV Rating Scale (ADHD-RS) — 19.06; 16.56; 17.51; 15.55 score on a scale — p=.20
Pharmacokinetics
Primary: Cmax of Proellex — 485.6; 876.7; 912.9; 1322.5 ng/mL
Fertility
Primary: Implantation Rate — 30.1; 35.3 % of sacs per embryo transferred
Prediabetes
Primary: Vascular Endothelial Function — -195.9; -6.181; -5.629 %*min
Pain
Primary: Pain Score Using Five Scales — 15; 0; 5; 0 Participants
Renal Cell Carcinoma
Primary: Duration of Sunitinib and Pazopanib Treatment in Participants — 171; 114.5 days
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Mean Change From Baseline in Post-dose Trough FEV1 — -0.029; -0.003 Liters — p=0.0404
Aortic Stenosis · Brain Infarction · Cerebrovascular Accident
Primary: Percentage of Participants With Freedom From Clinical or Radiographic Central Nervous System (CNS) Infarction — 74.4; 68.0; 67.6 percentage of participants — p=0.22
Prediabetes · Cardiovascular Disease
Primary: Vascular Endothelial Function — -294.4; -152.9; -102.9; -361.6 %FMD*min
Allergic Rhinoconjunctivitis
Primary: Variation of the Concentration of Phleum Pratense Extract Needed to Produce a Positive Nasal Provocation Test From Baseline (V0) to Final Visit (FV). — 0.493; 0.275…
Attention Deficit Hyperactivity Disorder (ADHD)
Primary: ADHD-IV Rating Scale (ADHD-RS) — 28.50; 20.91; 18.63 score on a scale — p=<.0001
Myelofibrosis
Primary: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) up to 5 Years — 2153; 830 Participants