65,437 trials
Adenocarcinoma · Colorectal Cancer · Ovarian Cancer
Primary: Number of Participants With Complete Responses (CRs), Partial Responses (PRs,) Stable Disease and Progressive Disease in the Ovarian Cancer and Breast Cancer Cohorts…
Degenerative Disc Disease
Primary: Number of Participants With Fusion — 50 Participants
Major Depressive Disorder · Depression
Primary: Montgomery-Asberg Depression Rating Scale Comparison to Baseline — 29.50; 15.83 units on a scale
Muscular Atrophy
Primary: The Percent Change in Bilateral Thigh Lean Mass Density (Grams) as Measured by DEXA Scan Will be Compared Between Baseline and After 5-days of Bed Rest — -3.845; -0.249…
Refractive Error · Presbyopia
Primary: Percentage of Subjects With Investigator-graded Lens Centration of "Optimal" — 97.0; 91.0 percentage of subjects — p=0.0455
Psoriatic Arthritis
Primary: Proportion of Patients Achieving American College of Rheumatology 20 (ACR20) Response Criteria on Secukinumab Versus Placebo at Week 24 — 58; 67; 22 Participants
Chronic Disease
Primary: Accelerometer-based Moderate-to-vigorous Physical Activity (MVPA) — 144.4; 129.9 minutes/week — p=.03
Pancreatectomy
Primary: Overall Pain in Postoperative Period — 1.6; 2.7 score on a scale — p=0.1459
Avian Influenza
Primary: Number and Percentage of Subjects Achieving a Hemagglutination Inhibition (HAI) Titer of ≥1:40 — 0; 0; 0; 0 Participants
Low-Grade Lymphoma
Primary: Number of Participants With Objective Response — 1; 2; 14; 6 Participants
Postoperative Pain
Primary: Visual Aanalog Scale (VAS) for Pain Assessment With Cough at 48 Hours — 1.7; 3.9 units on a scale — p=.0022
Degenerative Disc Disease
Primary: Percentage of Participants With Fusion — 99.1 Percentage of Participants
Herpes Zoster · Herpes Zoster-related Complications
Primary: Geometric Mean Fold Rise (GMFR) in Varicella-Zoster (VZV) Antibody Responses Measured by Glycoprotein Enzyme-linked Immunosorbent Assay (gpELISA) — 2.35; 1.28; 1.37…
Non-Cystic Fibrosis Bronchiectasis
Primary: Bacterial Clearance Rate of Sputum — 38; 16 Participants
Chorea Associated With Huntington Disease
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAEs), Serious TEAEs, Severe TEAEs, Drug-Related TEAEs, and TEAEs Leading to Withdrawal During Entire…