65,437 trials
Smoking
Primary: Number of Participants With Cotinine-Validated Abstinence From Smoking — 36; 30 Participants
Multiple Sclerosis
Primary: Placebo-Controlled Phase: Time to Confirmed Disease Progression (CDP) Confirmed After At Least 3 Months (Number of Participants With CDP After At Least 3 Months) — 73…
Genetic Disorders
Primary: Number of Patients That Receive Carrier Testing and Have Results to Return — 9; 155 Participants
Correction of Nasolabial Folds
Primary: Incidence of Device-related Adverse Events — 16 Participants
Rheumatoid Arthritis
Primary: Percentage of Participants Achieving 20% Improvement in American College of Rheumatology Criteria (ACR20) — 28.3; 58.6 percentage of participants — p=0.001
Episodic Cluster Headache
Primary: Overall Mean Change From Baseline in Number of Weekly Cluster Headache Attacks — -5.22; -8.69 Cluster Headache Attacks per Week — p=0.036
Esophageal Cancer · Gastroesophageal Junction Cancer
Primary: 2-month Progression-free Survival (PFS) of Sorafenib in Patients With Metastatic or Recurrent Esophageal and Gastroesophageal (GE) Junction Cancer. — 20; 14; 1…
Surgical Acute Wounds
Primary: Percentage of Patients With Complete Healing (100% of Epithelialization). — 77; 67 Participants
Bipolar Depression
Primary: The Montgomery-Asberg Depression Rating Scale (MADRS) — 31.95; 9.95; 10.95 score on a scale — p=<.001
Healthy
Primary: Number of Participants With One or More Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug Administration — 0; 0; 0; 0 Participants
Obsessive Compulsive Disorder
Primary: Yale-Brown Obsessive Compulsive Scale, Child Version (CYBOCS) — 28.20; 29.0; 26.67; 27.11 units on a scale
Heart Failure
Primary: Peak VO2 — 13.4; 13.8; 13.7; 13.6 ml/kg/min — p=0.2650
Migraine
Primary: Change From Baseline in Mean Monthly Migraine Days at Months 4, 5 and 6 — 0.06; -1.19; -2.25; -1.83 Days — p=<0.001
Cocaine Dependence
Primary: Subjective Stress Response TSST — 5.33; 5.28; 2.05; 2.13 units on a scale
Tobacco Dependence
Primary: 12-month Abstinence — 21; 6 Participants — p=<0.01