Phase 2 N=35 Dose Ranging Study of Carbidopa-levodopa
Age-related Macular Degeneration
Primary: Change in Best Corrected Visual Acuity by Early Treatment Diabetic Retinopathy Study Chart Visual Scale Testing — 4.5 Change in letters (BCVA)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=1,177 A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic Pulmonary Fibrosis
Primary: Absolute Change From Baseline in Forced Vital Capacity (FVC) [mL] at Week 52 — -183.48; -138.60; -114.65 Milliliters (mL) — p=0.0222
N/A N=44 Development/Testing of SUMMIT: a Tool to Help Patients Manage Pain While Tapering Opioids
Chronic Pain
Primary: Daily Morphine Milligram Equivalents (MME) — 25.1; 21.9 Morphine milligram equivalents per day — p=.91
Phase 3 N=165 A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial Hypertension
Primary: Participants >=2 Years of Age: Observed Steady-State Trough (Pre-dose) Plasma Concentration of Macitentan and Aprocitentan (Active Metabolite) at Week 12 Based on Body…
N/A N=374 Tailored vs. Anatomical Ablation Strategy for Persistent Atrial Fibrillation
Atrial Fibrillation
Primary: Number of Participants Free From Documented AF After One Ablation Procedure — 158; 124 Participants
N/A N=54 Monocentric Randomized Study, Assessing the Interests of the Determination of Vitamin D in Prison Population. (Vitamine D)
Male Prisoner
Primary: Dosage of Vitamin D — 28.2; 14.6 ng/mL — p=<0.001
Phase 3 N=42 Dexamethasone for Post Uterine Artery Embolization Pain
Leiomyoma
Primary: Pain Scores Using the VAS Questionnaire — 0.8; 1.3; 4; 6.1 score on a scale
Phase 2 N=20 Carbidopa-levodopa in Neovascular AMD
Age-related Macular Degeneration
Primary: Change in Best Corrected Visual Acuity — 6.0; 4.6 Change in letters (BCVA)
N/A N=75 Evaluating Technology Enabled Services in Perinatal Depression
Depression
Primary: Depression — 6.42; 6.55 score on a scale
Phase 2 N=93 Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate Cancer
Prostate Cancer
Primary: Percentage of Participants With 2-Year Progression-Free Survival (PFS) — 38; 61 Percentage of participants
N/A N=115 Telemedicine to Improve Use of Therapeutic Hypothermia in Rural Settings
Neonatal Encephalopathy
Primary: Time to Initiation of Therapeutic Hypothermia — 4.5 hours
Phase 3 N=1,367 Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)
Ovarian Cancer · Fallopian Tube Cancer · Peritoneal Neoplasms
Primary: Progression-Free Survival (PFS) Per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as Assessed by the Investigator in Participants With Programmed…
N/A N=86 VerTouch Device: A Prospective Randomized Controlled Trial
Pregnancy · Pain
Primary: Number of Redirections of the Needle — .72; 2.81; 2.35 Number of redirections of needle
Phase 3 N=224 PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge
Social Anxiety Disorder
Primary: Subjective Units of Distress Scale (SUDS) Score — 77.7; 78.2; 62.3; 61.3 score on a scale — p=.5063
N/A N=112 Co-Use of Opioid Medications and Alcohol Prevention Study
Alcohol Drinking · Opioid Use
Primary: Alcohol Use Reductions — 11; 12; 1; 1 Participants