65,437 trials
Respiratory Syncytial Virus (RSV)
Primary: Geometric Mean Titers (GMTs) of the Serum Anti-RSV Neutralizing Antibody (NAb) Titers — 864; 914; 843; 234 Titers
Head and Neck Squamous Cell Cancer
Primary: Initial Overall Survival (OS) for All Participants — 8.4; 7.1 Months — p=0.03160
Pain
Primary: Number of Patients Who Had Adequate Analgesia — 51; 172; 9; 35 Participants
Psoriasis · Plaque Psoriasis
Primary: Proportion of Subjects Who Achieve a Psoriasis Activity and Severity Index (PASI75) Response at Week 16 — 6.5; 66.5; 75.8 percentage of participants — p=<0.0001
Hallux Valgus
Primary: Average Postoperative Numeric Rating Scale (NRS) for Pain — 2.0; 1.9 units on a scale — p=0.596
Constipation
Primary: Spontaneous Bowel Movement (SBM) Frequency at Week 1 — 3.6; 5.0 SBMs/week — p=0.003
Brain Injury, Chronic
Primary: Computer Cognitive Test Scores - ImPACT Verbal Memory — 70.48; 74.21; 78.12; 75.36 units on a scale
PTSD
Primary: Clinician Administered PTSD Scale (CAPS) — 48.08; 52.39; 31.75; 34.43 units on a scale — p=.968
Osteoarthritis, Knee · Osteoarthritis, Hip
Primary: Change in Lower Extremity Functional Scale — 5.3; -1.6 Units on a scale
Drug Use · Alcohol Use · Congestive Heart Failure
Primary: Change in Substance Use Rates From Baseline — 51.37; 51.38; 35.53; 26.65 Days of Substance Use
Functional Dysphagia · Ineffective Esophageal Motility
Primary: Change in Distal Contractile Index (DCI) on High Resolution Esophageal Manometry — 241.9; 340.4 mm Hg
Tricuspid Valve Insufficiency
Primary: Mean Gradient Across the Tricuspid Valve — 1.3; 2.0; 1.9 mmHg
Carcinoma, Non-Small-Cell Lung
Primary: Kaplan Meier Estimate of Progression-Free Survival (PFS) as Assessed by the Investigator — 3.2; 4.5; 4.2 months
Healthy Volunteers
Primary: Efficacy: Percent Change From Baseline in Anti-fXa Activity at 2 Mins Following Andexanet/Placebo Administration — -7.06; -67.79; -78.51; -95.04 Percent change in…
Diphtheria · Tetanus · Acellular Pertussis
Primary: Anti-diphteria (Anti-D) and Anti-tetanus (Anti-T) Antibody Concentrations — 6.784; 6.493; 18.937; 18.515 IU/mL