65,437 trials
Healthy
Primary: Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve From Zero to Infinity (AUC[0-∞]) — 3080; 2880; 3110; 3120 Nanograms*hour/milliliter (ng*hr/mL)
Device Latency
Primary: Accuracy of Placebo-embedded IEM Detection by the MIND1 System Measured by the Percentage of Participants With IEM Detection Reported for Each of the 4 Time Points — 28…
Anxiety
Primary: State-Trait Anxiety Inventory-State Scores — 37.9; 40.7; NA; 37.7 units on a scale
Type 2 Diabetes · Overweight · Obesity
Primary: Change in Body Weight — 3.0; 0.3 kg
Liver Neoplasms
Primary: Sensitivity: Percentage of True Positive Lesions Among All Malignant Lesions Per Truth Standard — 48.7; 86.6; 35.3; 75.6 Percentage of true positive lesions — p=<.0001
Iron Deficiency Anaemia · Inflammatory Bowel Disease · Ulcerative Colitis
Primary: Change in Haemoglobin (Hb) Concentration From Baseline to Week 12 (Full Analysis Set, FAS) — 2.26; 0.01 g/dL — p=< 0.0001
Chronic Low Back Pain
Primary: Change in Numeric Rating Scale of Pain Intensity — -0.77; -0.84; -1.23; -1.00 units on a scale — p=0.007
Hypoxia
Primary: Time to First Event: Pulse Oximetry at 95%, or Successful Intubation — 106; 169 seconds
Diabetes Mellitus, Type 1
Primary: Number of Participants With Dose Limiting or Intolerable Treatment Related Adverse Events (AEs) — 0; 0; 0; 0 participants
fMRI · Alcohol Drinking · Alcoholism
Primary: Alcohol Infusions Self-administered — 10.45; 8.80 Number of alcohol infusions
Ovarian Cancer · Fallopian Tube Cancer · Peritoneal Cancer
Primary: Disease Progression According to RECIST Version 1.1, as Assessed by the Investigator, or Death From Any Cause (Investigator Progression Free Survival as Per invPFS)…
Anti-biotic Resistance
Primary: Oral L. Rhamnosus HN001 Therapy Compared to Placebo on Gastrointestinal and Extra-gastrointestinal Colonization of S. Aureus. — 9; 17; 25; 24 Participants
Acute Upper Respiratory Infections
Primary: Average Illness Duration (the Interval Between the Start of the Trial Treatment and the Time When Recovery/Improvement - Based on Patient Diary Data) — 87.7; 103.3 hours…
POSTOPERATIVE PAIN
Primary: Time Taken to Perform the Block — 2.4; 12.1 minutes — p=<0.001
Healthy
Primary: Mean Time Matched Placebo-Adjusted Changes From Baseline For Fridericia's Corrected QT Interval (ΔΔQTcF) — 1.4; 3.3; 0.2; -2.1 Millisecond (msec)