65,437 trials
High Flow Nasal Cannula
Primary: Percent Change in Pressure-rate Product (PRP) as a Function of Increasing HFNC Flow Rate on Both Types of HFNC Delivery System (FP and VT) — -10; -20; -23 percent change…
Tinea Pedis
Primary: Proportion of Patients in Each Active Treatment Group Who Are Considered a Therapeutic Cure — 96; 81 Participants
Metastatic Pancreatic Ductal Adenocarcinoma
Primary: Objective Response Rate (ORR) in All Patients Using Investigator Assessments According to Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) — 3.1; 0…
Essential Tremor · Parkinson's Disease
Primary: Positive Percent Agreement of Blinded Visual Assessment of Each Participant's DaTscan Image - Intent-to-diagnose (ITD) Population — 86.0; 84.2; 78.9; 86.0 Positive…
Healthy Volunteers
Primary: Pharmacokinetics (PK): Maximum Concentration (Cmax) of LY2835219 — 134; 10.5 nanogram per milliliter (ng/ml)
Influenza
Primary: Number of Subjects Boosted at Month 12 With Haemagglutinin-inhibition (HI) Antibody Concentrations Above the Cut-off Value — 178 Participants
Femoro Acetabular Impingement · Pain, Postoperative · Hip Labral Tear
Primary: Change in Patient Satisfaction and Functional Outcome — 64.5; 62.7; 74.6; 72.8 units on a scale — p=0.67
One-Lung Ventilation
Primary: Correlation Between Blood and End-tidal Isoflurane or Sevoflurane Concentration During One-lung Ventilation — 0.0807 Correlation coefficient
Neoplasm · Neoplasm Metastasis
Primary: Pharmacokinetics (PK): Area Under the Concentration Time Curve From Zero to Infinity (AUC[0-∞]) of Abemaciclib — 2230; 6850 nanogram*hour/milliliter(mL) ng*h/mL
Influenza
Primary: Number of Participants With Seroprotection to Influenza Vaccine Antigens at Day 0 (Pre-vaccination) and Day 21 (Post-vaccination) — 41; 37; 60; 60 Participants
Hepatitis B
Primary: Number of Participants With Any Non-serious Adverse Event (AE); Any Serious AE (SAE); Any AEs Leading to Discontinuation of Study Treatment (AELD) in Part 1 — 4; 3; 2; 3…
Hypoxemia · Trauma · Acute Myocardial Infarction
Primary: Oxygen Concentration Measured at the Lips by Datex-Ohmeda Differential Paramagnetic Sensor — 66.6; 97.1; 81.2; 81.2 percentage of oxygen
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline in Trough Forced Expiratory Volume in One Second (FEV1) at Day 28 in Intent-To-Treat (ITT) Population — 0.027; 0.035 Liters — p=0.57
Poliomyelitis · Diphtheria · Haemophilus Influenzae Type b
Primary: Antibody Concentrations for Pertussis Toxoid (Anti-PT), Filamentous Hemagglutinin (Anti-FHA) and Pertactin (Anti-PRN). — 43.2; 48.3; 24.2; 106.3 IU/mL
Sjogren's Syndrome
Primary: Percentage of Participants With a Clinically Relevant Decrease in European League Against Rheumatism (EULAR) Sjogren's Syndrome Disease Activity Index (ESSDAI) Score…