12,372 trials
Cerebral Palsy · Spasticity
Primary: MP: Change From Baseline in Ashworth Scale (AS) in UL Primary Clinical Target Pattern at Week 4 — -0.93; -1.15; -0.96; -1.02 Unit on a scale — p== 0.017
Neovascular Age Related Macular Degeneration
Primary: The Safety of Brolucizumab 6 mg Delivered in Prefilled Syringe in Patients With Neovascular Age Related Macular Degeneration — 0; 0 Participants
Nasal Polyposis
Primary: Change From Visit 1 at End of Study in Bilateral Nasal Polyp Grade Using Endoscopic Video — -0.7 units on a scale
Coronary Artery Disease · Sternal Pain
Primary: Opioid Consumption — 40.8; 49.1 Milligram Morphine Equivalents (MME)
Nervous System Diseases
Primary: Percentage of Participants With Response Rate — 80.0 Percentage of participants
Hemophilia B
Primary: Percentage of Participants With Confirmed Inhibitor Development as Measured by the Nijmegen-Modified Bethesda Assay — 3.03 percentage of participants
Macular Degeneration
Primary: Percentage of Participants With Stable Vision at Week 52 — 94.8; 91.3; 96.0 percentage of participants
Osteoarthritis
Primary: Number of Participants With Surgeon's Assessment of Procedural Difficulty — 9; 49; 8; 66 Participants
Parkinson Disease, Off Episodes
Primary: Mean Change From Pre-Dose to 30 Minutes Post-Dose in The Movement Disorders Society Unified Parkinson's Disease Rating Scale Part III Motor Examination (MDS-UPDRS Part…
Contraception
Primary: 6-Month (183 Days) Cumulative Pregnancy Percentage — 10.0; 10.5 pregnancy percentage
Uremic Pruritus
Primary: Change From Baseline in the Weekly Mean of the Daily 24-hour Worst Itching Intensity NRS Score During Week 8 — -3.8; -2.8; -3.2; -1.9 score on a scale — p=<0.001
Macular Degeneration
Primary: Percentage of Participants With Stable Vision at Week 52 — 91.7; 91.2; 95.5 percentage of participants
Parkinson's Disease
Primary: Rate of Clinical Decline — 11.116; 9.860 score per year — p=0.183
Hyperphosphatemia
Primary: Change From Baseline in Serum Phosphorus at Week 8 — 2.090; 2.095; 0.010; -0.200 mmol/L — p=<0.0001
Infections, Streptococcal · Streptococcus Pneumoniae
Primary: Person Year Rate as Regards Subjects With Culture-confirmed IPD Due to Any of the 10 Pneumococcal Vaccine Serotypes. In Children Starting Vaccination Within 7 Months of…