65,437 trials
Aging
Primary: Leg Blood Flow as Measured by Doppler Ultrasound — 174.99; 102.08; 428.45 ml/minute
Colorectal Adenomatous Polyps
Primary: Rectal Epithelial Cell Proliferation — 19.3; 20.3; 18.9; 16.8 percentage of cells positive
Smoking Cessation · Nicotine Dependence
Primary: 7-day Point-prevalence Smoking Abstinence — 2; 10 participants — p=<0.05
HIV-2 Infection
Primary: Death — 0 Participants
Psoriasis
Primary: Psoriasis Severity — 4.25 units on a scale
Chronic Obstructive Pulmonary Disease
Primary: Mean Change in 24 Post Dose Trough Forced Expiratory Volume in 1 Second (FEV1) — 0.0477; 0.1009; 0.0648; 0.0632 liters — p=0.0003
Pelvic Inflammatory Disease (PID)
Primary: Number of Participants With Positive Sexually Transmitted Infection Test (STI) — 6; 13 Participants — p=0.070
Single Ventricle Fontan Palliation
Primary: Change in VO2 Max — 1.33; 0.745 Change in ml/kg min
Knee Osteoarthritis
Primary: Pain on the Numeric Rating Scale (NRS) Change From Baseline to Study Conclusion — -1.96; -0.85 units on a scale
Adenoid Cystic Carcinoma
Primary: Determine the Objective Tumor Response Rate Following Treatment With TKI258 — 2; 22; 10 Participants
Hypothermia
Primary: Core Body Temperature — 36.8; 36.8 degrees Celsius — p=0.807
Postoperative Pain
Primary: Postoperative Pain Score on the Scale of 10 (0=No Pain and 10=Worst Pain) — 2; 2 units on a scale — p=0.252
Prematurity
Primary: Suck Rate and Efficiency: Change From Pre-test (Day 0) to Post-test (Day 5) — 2.0; 0.9 mL/min
Metastatic Breast Cancer
Primary: Percentage of Patients With a 2 Year Disease-Free Survival (DFS) as a Measure of Efficacy — 56; 83; 73 percentage of patients
Conductive Hearing Loss · Conductive and Sensori-neural Hearing Loss in the Same Ear · Unilateral, Profound Sensori-neural Hearing Loss
Primary: Holger's Scale — 29; 0; 1; 29 participants