Phase 4 N=17 Study of Brain Response to Emotional Pictures Using a Magnetic Resonance Imaging (fMRI) While on Escitalopram
Major Depression
Primary: 17-item Hamilton Depression Rating Scale (HAM-D) — 18; 19; 6; 6 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=46 FMRI Study of Brain Response Before and After Lithium Treatment in People With Bipolar Disorder
Bipolar Disorder
Primary: 17-item Hamilton Depression Rating Scale (HDRS) — 20; 6; 6; 2 units on a scale
Phase 4 N=29 A Multi-centre Evaluation of the Performance of Window Dressings on Subjects With High Risk Pressure Ulceration
Pressure Ulcer
Primary: Erythema ( No/Yes) — 5; 24; 16; 13 participants
Phase 4 N=57 Liposomal Bupivacaine in Total Shoulder Arthroplasty
Pain
Primary: Pain Levels — 4.8; 4.0; 4.7; 4.0 units on a scale — p=<0.05
Phase 4 N=93 Varenicline for Light Smokers
Smoking
Primary: Point Prevalence Smoking Outcome at 12 Weeks (End of Treatment) — 24; 7 participants — p=<0.001
Phase 4 N=21 Switching From Oral Dopamine Agonists to Rotigotine
Restless Legs Syndrome · Ekbom Syndrome · Willis-Ekbom Disease
Primary: Proportion of Patients Completing the Switch and Their Adverse Events — 17; 14; 3 participants
Phase 4 N=468 Assessment of Patients Treated With JETREA® for Vitreomacular Traction
Vitreomacular Traction · Vitreomacular Adhesion
Primary: Proportion of Subjects With Nonsurgical Resolution of Focal Vitreomacular Traction (VMT/VMA) at Day 28, as Determined by Central Reading Center (CRC) Spectral Domain…
Phase 4 N=171 Optimal Dosing of Ketamine for Procedural Sedation and Analgesia in Children
Moderate, Deep Sedation
Primary: Sedation Efficacy — 5.5; 6; 6 units on a scale — p=0.2
Phase 4 N=20 A Pilot Study to Determine the Feasibility and Utility of Implementing of the Full Scale TOM Trial
Asthma
Primary: Asthma Control Test — 17.5; 13; 12; 10 units on a scale
Phase 4 N=153 Does Treatment With Macrobid Reduce Urinary Tract Infections in Patients Receiving a Sub-Urethral Sling for Incontinence
Stress Incontinence
Primary: Incidence of Post-operative UTI Following the Placement of Sub-urethral Sling for the Treatment of Stress Urinary Incontinence — 13; 24 participants
Phase 4 N=180 New Stage 1 Formula on Gut Comfort and Gut Health
Health Behavior
Primary: Stool Frequency — 2.2; 2.2; 2.3; 1.6 Times per day
Phase 4 N=24 Effects of Pitavastatin on Lipid Profiles in HIV-infected Patients With Dyslipidemia and Receiving Atazanavir/Ritonavir
HIV · Dyslipidemia
Primary: Efficacy of Pitavastatin in HIV-infected Patients With Dyslipidemia and Receiving Atazanavir/Ritonavir — 239.9; 257.6; 282; 350 mg/dL — p=<0.05
Phase 4 N=79 Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department
Anxiety · Lacerations
Primary: Intention to Treat (ITT): Modified Yale Preoperative Anxiety Score (mYPAS) — 59.9201; 46.2871 units on a scale — p=0.026
Phase 4 N=101 Eribulin Mesylate Phase IV Clinical Trial in Korean Patients With Metastatic or Locally Advanced Breast Cancer
Breast Neoplasms · Breast Cancer
Primary: Number of Participants With Any Treatment-emergent Adverse Event (TEAE) and Any Treatment-emergent Serious Adverse Event (SAE) — 101; 20 Participants
Phase 4 N=36 Ictal and Interictal Inflammatory Markers in Migraine
Migraine
Primary: Change in the Total Serum Adiponectin (T-ADP) — -0.96; 0.25; -0.97; 0.29 ug/mL