Phase 2 N=8 Botulinum Toxin for the Management of Chronic Orchialgia
Chronic Testicular Pain
Primary: Visual Analog Scale for Pain Score — 59.3; 30.3; 55.0; 75.0 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=50 Carboplatin/Pralatrexate in Recurrent Platinum-Sensitive Ovarian, Fallopian or Primary Peritoneal Cancer
Ovarian Cancer · Fallopian Tube Cancer · Peritoneal Cancer
Primary: Maximum Tolerated Dose (MTD) — 105 mg/m^2
N/A N=377 Age of Red Blood Cells in Premature Infants Study (ARIPI)
Premature Birth
Primary: 1. Composite Outcome of Necrotizing Enterocolitis, Intraventricular Hemorrhage, Bronchopulmonary Dysplasia and Retinopathy of Prematurity at 30 and 90-days. 2. Mortality…
Phase 3 N=443 Open-Label, Long-term Balsalziade Disodium Tablet Ulcerative Colitis Study
Inflammatory Bowel Disease · Ulcerative Colitis
Primary: Incidence of Treatment Emergent AEs — 273 participants
Phase 4 N=105 Sedation Methods During Cataract Surgery
Phacoemulsification · Cataract
Primary: Eye Mobility During Surgery (See Link to Study Protocol for Scale) — 1.39; 1.41; 1.31 units on a scale
N/A N=204 Safety & Prevention Outcomes Study
Drug Overdose · Opioid-Related Disorders
Primary: Overdose Risk Behavior — -1.54; -0.51 Scores on a scale
Phase 2 N=4 Proof-of-Concept Safety Study of CPP-109 (Vigabatrin) for Treatment Refractory Tourette's Disorder
Tourette's Disorder
Primary: Global Severity Score on the Y-GTSS — 80.25; 78.75; 61; 69.75 units on a scale
N/A N=20 Innovations in HIV Testing (TI)
Human Immunodeficiency Virus
Primary: Qualitative Summaries of Participant Experience in Focus Group Discussions — 100; 7; 26; 10 number of times reported in FGD
Phase 2 N=178 Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma
Brain and Central Nervous System Tumors
Primary: Progression-free Survival Rate at 3 Years — 92.2; 93.7; 58.8 percentage of participants
Phase 4 N=570 Extended-Release Naltrexone vs. Buprenorphine for Opioid Treatment
Opioid Use Disorder
Primary: Time to Relapse (Intent to Treat Population) — 8.4; 14.4 weeks
Phase 2 N=127 Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?
Ventral Hernia · Umbilical Hernia · Incisional Hernia
Primary: Post-operative Opioid Use — 10.59; 15.62; 16.09; 32.24 mg
N/A N=23 Weightbearing Assessment of Tarsal Instability
Adult-acquired Flatfoot Disorder (AAFD)
Primary: Change in Joint Motion Between Touch-down Bearing Navicular and Full-weight Bearing Navicular — 3.56; 4.36; -0.1666; -0.170 mm
Phase 3 N=103 Altitude Sickness Prevention and Efficacy of Comparative Treatments
Acute Mountain Sickness
Primary: Number of Participants With Acute Mountain Sickness — 24; 22; 15 Count of participants
Phase 3 N=527 A Moderate to Severe Rheumatoid Arthritis Study
Rheumatoid Arthritis
Primary: Percentage of Participants Achieving American College of Rheumatology 20% (ACR20) Response - Placebo Versus Baricitinib 4 mg — 27.3; 55.4 Percentage of Participants…
Phase 3 N=507 Comparison of SAR342434 to Humalog as the Rapid Acting Insulin in Adult Patients With Type 1 Diabetes Mellitus Also Using Insulin Glargine
Type 1 Diabetes Mellitus
Primary: Change in HbA1c From Baseline to Week 26 — -0.42; -0.47 percentage of HbA1c