N/A N=40 Probability Ramp Control of Propofol for EGD
Gastrointestinal Disease
Primary: Number of Participants Requiring Adjustment in Propofol Dosing — 16; 2 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=51 Two Phase Clinical Study of the Impact of Contact Lenses and Solutions on Corneal Structure
Normal Contact Lens Wear
Primary: HRT Corneal Scan — 85; 66; 49; 63 cells/mm^3
Phase 2 N=80 Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantation
Acute Myelogenous Leukemia · Acute Lymphocytic Leukemia · Myelodysplastic Syndrome
Primary: Percentage of Participants With Grades II to IV aGVHD at Day +100 of Atorvastatin Administration — 30 percentage of patients
N/A N=37 Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
Obesity · Vitamin D Deficiency
Primary: Vitamin D Concentrations, Pre Operative and Post Bariatric Surgery Following 12 Weeks of Vitamin D Supplementation — 19.1; 27.2 ng/mL — p=< 0.001
Phase 4 N=1,366 VERtebral Fracture Treatment Comparisons in Osteoporotic Women
Postmenopausal Osteoporosis
Primary: Proportion of Participants With New Vertebral Fractures — 28; 64 Participants (with at least one event) — p=0.000094
Phase 4 N=35 COMFORT: A Multicenter, Open-label, Randomized, Crossover Study
Varicose Veins
Primary: Pain — 11.3; 9.5 units on a scale
Phase 4 N=36 Biomarker Study of Acamprosate in Schizophrenia
Schizophrenia · Schizoaffective Disorder
Primary: Anterior Cingulate Cortex - Choline — 1.64; 1.54; 1.46; 1.58 mM
Phase 3 N=1,846 Study to Evaluate Efficacy, Safety, and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Vaccine GSK1437173A
Herpes Zoster
Primary: Number of Subjects With Confirmed Herpes Zoster (HZ) Episode — 49; 135 Participants — p=<0.0001
Phase 3 N=1,143 Efficacy and Safety of FIAsp Compared to Insulin Aspart Both in Combination With Insulin Detemir in Adults With Type 1 Diabetes
Diabetes · Diabetes Mellitus, Type 1
Primary: Change From Baseline in HbA1c (Glycosylated Haemoglobin) — 7.62; 7.63; 7.58; 7.31 Percentage of glycosylated haemoglobin
Phase 3 N=562 Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme
Brain and Central Nervous System Tumors
Primary: Overall Survival — 9.33; 7.62 Months
N/A N=23 Clinical Outcomes of Buffered vs. Non-Buffered Lidocaine
Blood Levels of Buffered vs Non-buffered Lidocaine · Anesthetics, Local
Primary: Lidocaine Blood Levels 30 Minutes Post Injection — 7.9; 15.8 ug/L — p=0.006
Phase 3 N=142 D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)
Obsessive-compulsive Disorder
Primary: Children's Yale-Brown Obsessive-Compulsive Scale. — 13.53; 13.98 units on a scale
Phase 2 N=13 Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp
Dystonia
Primary: Using a Patient Rated Subjective Scale (Visual Analogue Scale), Change From Baseline With Botulinum Toxin Therapy Plus Occupational Therapy Compared to Botulinum Toxin…
Phase 2 N=41 Phase 2a RDEA3170 and Allopurinol Combination Study in Gout Subjects
Gout
Primary: Cohort 1 - Maximum Percentage (%) Change in Serum Urate of Multiple-dose RDEA3170 Administered in Combination With Allopurinol (Emax, CB (%)) — -40.2; -55.0; -56.8…
N/A N=95 Impact Ureteral Sheath Design During Ureteroscopy
Renal Stone · Nephrolithiasis · Urolithiasis
Primary: Number of Participants With Successful Sheath Placement — 37; 39 Participants