65,437 trials
Rosacea
Primary: IGA of Improvement — 3.1; 3.5 units on a scale
Leukemia, Mast-Cell · Mantle-cell Lymphoma
Primary: Chronic Graft-vs-Host Disease (cGvHD) — 20 percentage of participants
Prostate Cancer
Primary: Effects of Selenium and Finasteride and Their Combination on PSA Level — 1.9; 1.9; 2.0; 2.1 ng/mL — p=0.5137
Asthma · Perennial Allergic Rhinitis
Primary: Number of Reported Adverse Events (AEs) — 9; 1; 1; 2 Events
Varicose Veins · Telangiectasis
Primary: Change From Baseline in Extent of Telangiectasias — 57.24; 76.08 percent of change negative values
Hepatic Impairment
Primary: Assessment of Maximum Observed Plasma Drug Concentration (Cmax) for Telotristat Ethyl and Comparison Between Each HI Group and Healthy Control Group — 4.06; 6.88; 9.99…
Adenoid Cystic Carcinoma
Primary: Overall Response Rate — 0; 3; 25; 4 Participants
Alzheimer's Disease
Primary: Change From Baseline in Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog) Total Score at Week 48 — 2.9; 1.6; 2.7; 3.1 Score on a scale — p=0.049
Hemophilia A
Primary: Model-Based Annualized Bleed Rate (ABR) for Treated Bleeds, Arm A: Emicizumab Versus Arm B: No Prophylaxis — 2.9; 23.3 treated bleeds per year — p=<0.0001
Hypertension · Left Ventricular Diastolic Dysfunction
Primary: Improvement in Exercise Tolerance — 9; 8 Participants
Refractive Error
Primary: Binocular High Contrast/High Illumination (HC/HI) Visual Acuity (VA) at Intermediate Distance (80 cm) — -0.07; -0.09 logMAR
Dry Eye
Primary: Mean Change From Baseline in Global Ocular Discomfort Score at Day 71 — -7.9; -3.6 units on a scale
Chronic Hepatitis C Infection
Primary: Percentage of Part 1 Participants With Sustained Virologic Response 12 (SVR12) Weeks Posttreatment — 95.5 percentage of participants
Salivary Gland Cancer
Primary: Response Rate of ZD1839 in Patients With Advanced or Recurrent Salivary Gland Cancer Who Are Not Candidate for Curative Surgery or Radiotherapy — 0; 0; 18; 13 Participants
Non-Small Cell Lung Cancer
Primary: Percentage of Participants With Objective Response as Per Investigator Assessment According to Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v. 1.1)…