Phase 4 N=135 Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy
Procedural Sedation
Primary: Level of Sedation Throughout the Entire Procedure — 22; 9; 10; 1 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=60 Ease of Use and Microbial Contamination of Tobramycin Inhalation Powder (TIP) Versus Nebulised Tobramycin Inhalation Solution (TIS) and Nebulised Colistimethate (COLI)
Cystic Fibrosis
Primary: Mean Total Administration Time — 37.0; 16.4; 4.2; 5.0 minutes
Phase 4 N=21 Lipo-prostaglandin E1 Improves Renal Hypoxia Evaluated by BOLD-MRI in Patients With Diabetic Nephropathy
Diabetic Nephropathy
Primary: the Change of Tissue Content of Deoxyhemoglobin Assessed by BOLD-MRI — 22.04 1/ms
Phase 4 N=92 Ranitidin Versus Omeprazole in Patients Taking Clopidogrel
Coronary Artery Disease · Drug Interaction Potentiation
Primary: Comparing Platelet Function of Patients on Dual Antiplatelet Therapy With ASA + Clopidogrel, Between the Groups Ranitidin and Omeprazole, After One Week of Randomized…
Phase 4 N=281 The Effect of Liposomal Lidocaine on Perceived Pain in Children During Percutaneous Interosseous Pin Removal in the Outpatient Setting
Pain
Primary: Pain — 0.70; 0.88; 1.04; 0.87 units on a scale
Phase 4 N=29 A Trial Comparing Efficacy and Safety of Voriconazole Administered With Therapeutic Drug Monitoring vs. Standard Dosing
Fungal Infection
Primary: Number of Participants With Treatment Failure — 1; 5 participants
Phase 4 N=50 Efficacy of GXR as Adjunctive Therapy With Psycho-stimulant on Executive Function in Children With ADHD
Attention Deficit Hyperactivity Disorder
Primary: Effect of Adjunctive INTUNIV Extended Release Treatment on Executive Function as Assessed by Change From Baseline on the BRIEF-parent Questionnaires — -5.3; -6.9 units…
Phase 4 N=45 Study to Validate the Instructions for Use of TOBI® Podhaler™ in Cystic Fibrosis Patients
Cystic Fibrosis
Primary: The Use of the Approved US TOBI Podhaler Instructions for Use (IFU) to Communicates the Information Necessary to Achieve Safe and Effective Use of the Podhaler Device…
Phase 4 N=17 A Study of the Neurological Effects of Adding Maraviroc to HAART Regimen in Patients With HIV (HANDmac)
Human Immunodeficiency Virus (HIV) · HIV Associated Neurocognitive Disorders (HAND)
Primary: Change in Neurocognitive Functioning — -0.94; -0.81; -1.03; -0.51 Global Neurocognitive Z-Score — p=0.05
Phase 4 N=84 Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal Dose
Analgesia, Obstetrical · Cesarean Section
Primary: Dose of IT Morphine and IT Hydromorphone for Adequate Analgesia (Pain Score Less Than or Equal to 3) in 90% of Patients — 75; 150 micrograms
Phase 4 N=80 Analgesia After Total Shoulder Arthroplasty
Total Shoulder Arthroplasty
Primary: Numeric Rating Scale (NRS) Pain Score With Movement — 4.5; 3.4; 4.2; 4.9 units on a scale
Phase 4 N=10 A Study Of Pregabalin (Lyrica) Drug Levels In Urine, Plasma And Breast Milk Of Healthy Lactating Women
Healthy Lactating Women
Primary: Area Under the Curve From Time Zero to End of Dosing Interval (AUCtau) — 32.50 microgram*hour/milliliter (mcg*hr/mL)
Phase 4 N=130 Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery
Shoulder Injury
Primary: Duration of Sensory Blockade — 16.9; 18.2; 13.8 hours — p=0.001
Phase 4 N=175 Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVO
Retinal Vein Occlusion
Primary: Number of Participants With Adverse Events as a Measure of Safety and Tolerability — 35; 28; 45; 16 Participants
Phase 4 N=138 Does Tranexamic Acid Reduce the Need for Blood Transfusions in Patients Undergoing Hip Fracture Surgery?
Hip Fracture
Primary: Number of Participants Who Received a Hospitalization Transfusion — 18; 12 participants