17,261 trials
Non-small Cell Lung Cancer (NSCLC)
Primary: Number of Patients With Grade 3 and Grade 4 Treatment-related Adverse Events (TRAEs) — 7; 0; 7; 5 Participants
Myeloproliferative Disorders · Acute Myelogenous Leukemia · Chronic Myelogenous Leukemia
Primary: Number of Participants Who Experienced Transplant Related Mortality — 5; 4 Participants
Atopic Dermatitis
Primary: Proportion of Patients Achieving an Investigator's Global Assessment (IGA) of 0 (Clear) or 1 (Almost Clear) and a Decrease of at Least 2 Points in IGA at Week 8. — 0.12…
IgA Nephropathy
Primary: MCP-Mod Estimates of the Ratio to Baseline of Urine Protein to Creatinine Ratio (UPCR) (g/Mol) - Parts 1 and 2 at Day 90 — 0.85; 0.80; 0.76; 0.69 Ratio to baseline…
Alcohol Dependence · Alcohol Use Disorders · Alcohol Abuse
Primary: Drinking Quantity Per Day — 1.25; 1.38; 1.10 Standard drinks per day — p=0.51
Influenza
Primary: Number of Subjects With Influenza-like Clinical Illness and Laboratory Confirmed Infection Post Challenge With a Homologous A Strain Influenza Virus — 17; 19; 15…
Type 2 Diabetes
Primary: Fasting Insulin — 12.7; 13.1; 16.4; 13.9 μU/mL
Healthy Volunteers · Norovirus
Primary: Geometric Mean Blocking Titers 50 Percent (%) (GMBT50) of Anti-norovirus GI.1 VLP Antibodies as Measured by Histo-Blood Group Antigen HBGA Blocking Assay — 27.4; 18.3…
Hodgkin Lymphoma · Diffuse Large B-Cell Lymphoma
Primary: Progression Free Survival (PFS) — 6.6 months
Opioid-use Disorder · Alcohol Use Disorder
Primary: Peak Positive Subjective Responses to Placebo. — 3.3; 2.3 units on a scale
Asthma · Obesity
Primary: Change in Asthma Control Test Score — 2; 2.6 units on a scale
Central Nervous System Embryonal Tumor With Rhabdoid Features · Central Nervous System Embryonal Tumor, Not Otherwise Specified · Central Nervous System Ganglioneuroblastoma
Primary: Maximum Tolerated Dose (MTD) — 90; 85 mg/m^2
BRCA1 Gene Mutation · BRCA2 Gene Mutation · Ovarian Serous Adenocarcinoma
Primary: Incidence of Dose-limiting Toxicities (DLTs) Defined as the Rate of Drug-related Grade 3-5 Adverse Events Assessed Using the National Cancer Institute Common Terminology…
Transitional Cell Carcinoma
Primary: Overall Response Rate — 3; 6; 9; 7 Participants
Human Immunodeficiency Virus
Primary: Safety of Dapivirine (25 mg) Administered in a Silicone Elastomer Vaginal Matrix Ring in HIV-uninfected Postmenopausal Women, When Inserted Once Every 4 Weeks During 12…