N/A N=51 The Relationship Between Sleep and Glucose Tolerance in Prediabetes: the Role of GLP-1 in Short Sleepers
Prediabetes
Primary: GLP-1 Levels in Response to Oral Glucose Tolerance Test — 16.66; 18.57 pmol/l.h — p=0.209
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=12 Post-stroke Neural Plasticity With Atomoxetine
Atomoxetine Hydrochloride · Placebos
Primary: Change in Fugl Meyer Assessment — 9.3; 2.2; 11.9; 5.8 units on a scale
N/A N=274 Pathogenesis of Adverse Drug Reactions
Seizures
Primary: Drug (Valproic Acid or Carbamazepine) Metabolite Profiles in Urine — 15.2; 13.1; 1.15; 2.13 nmol per mg creatinine
Phase 2 N=45 Chemotherapy Response Monitoring With 18F-choline PET/CT in Hormone Refractory Prostate Cancer
Hormone Refractory Prostate Cancer
Primary: Metabolically Active Tumor Volume (MATV) Response — 20 Participants
Phase 3 N=322 Study of Buprenorphine Sublingual Spray for the Treatment of Moderate to Severe Pain
Pain
Primary: Numeric Rating Scale (NRS) Summed Pain Intensity Difference (SPID) Over 0 to 48 Hours After Time 0 (NRS SPID-48) — 89.40; 171.33; 125.58; 124.85 units on a scale…
Phase 4 N=40 Ethnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy Subjects
Healthy
Primary: Ethnic Differences in Burning Pain Induced by Topical Capsaicin — 0.81; 4.07; 17.05; 13.3 units on a scale — p=<0.05
Phase 2 N=79 Safety and Protective Efficacy of FF-3 Dry Powder in Healthy Subjects Infected With Influenza Challenge Strain
Influenza
Primary: Frequencies of Viral Shedding — 51; 22 Participants — p=0.1436
Phase 1 N=9 Human Mesenchymal Stem Cells For Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
Primary: Incidence of Pre-specified Infusion Associated Adverse Events — 0; 0; 0 participants
N/A N=16 Clinical Assessment of New Speaking Valve With Heat and Moisture Exchanger (HME) for Tracheotomized Patients
Tracheostomy
Primary: Evaluate Patient Experiences Associated With Exposure to the Speaking Valve With a Heat- and Moisture Exchanger (TW) for Tracheotomized Patients Based on Results From…
Phase 2 N=24 Doxorubicin-eluting LC Bead M1 for Patients With Hepatocellular Carcinoma
Hepatocellular Carcinoma
Primary: Success of DEBDOX-M1 Procedure as a Measure of Feasibility — 100 percentage of successful treatments
Phase 3 N=1,623 Study to Determine Efficacy and Safety of Lenalidomide Plus Low-dose Dexamethasone Versus Melphalan, Prednisone, Thalidomide in Patients With Previously Untreated Multiple Myeloma
Multiple Myeloma
Primary: Kaplan-Meier Estimates of Progression-free Survival (PFS) Based on the Response Assessment by the Independent Review Adjudication Committee (IRAC) — 25.5; 20.7; 21.2…
N/A N=120 Medication Adherence in Kidney Transplant Recipients Using Automated Reminders and Provider Notification
Medication Adherence
Primary: Immunosuppression (Tacrolimus) Adherence — 78; 88; 55 percentage of correct tacrolimus doses
Phase 2 N=12 Ketamine for Depression and Suicide Risk
Depression · Suicide
Primary: MADRS Total Score at Baseline and Last Acute Phase Observation — 29.4; 29.4; 29.4; 15.9 units on a scale — p=<0.01
N/A N=32 The Summer Camp Study: Blood Glucose Control With a Bi-Hormonal Bionic Endocrine Pancreas
Type 1 Diabetes
Primary: Difference in Average Blood Glucose (BG) Between Closed-loop (Bionic Pancreas Arm) and Open-loop (Insulin Pump Arm) Periods as Determined From All Scheduled HemoCue…
Phase 3 N=86 A Comparison of Midazolam and Zolpidem as Oral Premedication in Children
Parental/Caregiver Anxiety · Child's Anxiety
Primary: Patient Anxiety at the Time of Separation — 26.69; 30.00 units on a scale