N/A N=20,806 Evaluation of Green Dot a Primary Prevention Intervention
Sex Offenses
Primary: Average Number of Sexual Assault Events Used (Perpetrated) Per School. — 518; 420; 485; 472 Number of events per school — p=0.0003
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=106 Glutamine for the Treatment of Patients With Irritable Bowel Syndrome
Diarrhea-Predominant Irritable Bowel Syndrome
Primary: Change in the Irritable Bowel Symptom Severity Scale — 181; 301 units on a scale
Phase 3 N=120 Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia
Preeclampsia
Primary: Increase in Gestational Age in Days — 5.0; 6.0 days
Phase 3 N=62 Borage and Echium Seed Oils for Asthma
Asthma
Primary: Cellular Changes That Occur With Borage and Echium Seed Oil Supplementation — 5.06; 2.56 ng
Phase 2 N=40 Measuring the Amount of Methadone or Morphine in the Blood of Neonates, Infants & Children After Cardiac Surgery.
Pain
Primary: Maximum Concentration of Morphine Including Its Metabolites (Morphine-3-glucuronide and Morphine-6-glucuronide) — 27.55; 225; 22.95 ng/mL
Phase 4 N=41 Effects of Intravenous Acetaminophen on Body Temperature and Hemodynamic Responses in Febrile Critically Ill Adults
Fever · Critical Illness
Primary: Core Body Temperature — 38.4; 37.9 degrees Celsius — p=0.002
Phase 2 N=116 A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma
Multiple Myeloma
Primary: Phase 1: Number of Participants With Dose-limiting Toxicities (DLTs) — 0; 0; 1; 2 participants
Phase 2 N=45 Blinatumomab in Adults With Relapsed/Refractory Philadelphia Positive B-precursor Acute Lymphoblastic Leukemia
Relapsed/Refractory Philadelphia Positive B-precursor ALL
Primary: Percentage of Participants With Complete Remission/Complete Remission With Partial Hematological Recovery (CR/CRh*) During the First Two Treatment Cycles — 35.6…
Phase 3 N=1,986 Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
Major Depressive Disorder
Primary: Full Remission During the Randomised Treatment Period — 110; 95 participants — p=0.2641
Phase 4 N=97 Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique
Rotator Cuff Tear
Primary: Return to Function — 1257.45; 1106.31 units on a scale
N/A N=280 Individualized Analgesia After Adenotonsillectomy
Analgesia
Primary: The Percentage of Patients Requiring at Least One Medical Intervention for Respiratory Events — 16; 29 Participants — p=<0.05
Phase 4 N=160 Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures
Blood Loss · Anesthesia
Primary: Number of Participants Needing Intervention to Treat Blood Loss (a Composite of Use of Uterotonics, Re-aspiration, and Bimanual Massage) — 20; 13 Participants
N/A N=62 Reducing Obesity in Underserved Postpartum African American Women
Obesity
Primary: Feasibility as Measured by Attendance at Group Sessions and Barriers to Attendance (Logs Kept by Research Staff) — 9; 12; 11 participants
Phase 2 N=34 Fluocinonide Cream in Treating Symptoms of Vaginal Dryness and Painful Sexual Intercourse In Patients With Breast Cancer Undergoing Hormone Therapy
Breast Carcinoma
Primary: Change in Symptom Scores of Vaginal Dryness — -2 units on a scale — p=<0.001
Phase 2 N=183 Efficacy and Safety Study of Clonidine Lauriad® to Treat Oral Mucositis
Oral Mucositis
Primary: Cumulative Radiation Dose at Which Severe Oral Mucositis (World Health Organization [WHO] Score ≥ 3) Was First Observed — 66; 56; 48; 60 Cumulative radiation dose (Gy)…