Phase 4 N=69 Characteristics of Sleep Patterns in Young Adults With and Without Insomnia
Sleep Disorders
Primary: Change in Pittsburgh Sleep Quality Index — -0.86; -3.15; -3.32 difference score of PSQI total
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=49 RAD001 With Paclitaxel and Carboplatin in First Line Treatment of Patients With Advanced Large Cell Lung Cancer With Neuroendocrine Differentiation
Carcinoma, Large Cell · Neuroendocrine Tumors
Primary: Percentage of Participants Progression-free — 49.0 Percentage of participants
Phase 4 N=129 The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the US
Dental Plaque · Gingivitis
Primary: Dental Plaque Scores — 3.91; 3.86; 3.84 units on a scale — p=0.652
Phase 4 N=179 Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
Dental Plaque · Gingivitis
Primary: Dental Plaque Scores — 3.33; 3.22; 3.34 units on a scale — p=0.04
Phase 4 N=19 Study to Evaluate Effect of Pandel Cream 0.1% on HPA Axis in Pediatric and Adult Population
Psoriasis · Atopic Dermatitis
Primary: Post-injection Serum Cortisol Level — 1 participants
Phase 4 N=682 Determining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study)
Platelet Aggregation Inhibitors · Coronary Heart Disease
Primary: Changes in Platelet Function in Response to Clopidogrel — 38.51; 14.06 percentage of maximum aggregation change
Phase 4 N=60 Effect of Oral Choline Supplementation on Postoperative Pain
Postoperative Pain · Inflammation
Primary: Numerical Rating Scale (NRS) Pain Score — 5.8; 7.4; 7.4; 8.8 score on a scale
Phase 4 N=30 Nebivolol Effect on Nitric Oxide Levels, Blood Pressure, and Renal Function in Kidney Transplant Patients
Hypertension
Primary: Plasma Nitric Oxide Level Change From Baseline to Month 12 Between the Groups. — 11.47; -17.27 percent change
Phase 4 N=30 Effect of a Transcutaneous Electrical Nerve Stimulation (TENS) Device on Overall Facial Appearance
Ageing
Primary: Evaluate Overall Facial Improvement Assessed Live by the Investigator and Subjects Using the Global Aesthetic Improvement Scale (GAIS) at 12 Weeks Compared to Baseline…
Phase 4 N=132 Open Label Study to Assess the Predictability of Early Response to Certolizumab Pegol in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
Primary: The Percentage of Subjects With Clinical Response at Week 12 Who Also Had Clinical Response at Week 52 — 69.1 percentage of subjects
Phase 4 N=172 Strattice in Repair of Inguinal Hernias
Hernia, Inguinal
Primary: Change From Baseline in Activities Assessment Scale at 3 Months — -7.49; -6.12 units on a scale
Phase 4 N=170 Parallel-Group Study to Assess the Effect of Rasagiline on Cognition in Patients With Parkinson's Disease
Parkinson's Disease
Primary: Mean Change From Baseline to Week 24 in the Scales for Outcomes in Parkinson's Disease-Cognition (SCOPA-COG) Summary Score — 1.6; 0.8 units on a scale — p=0.2204
Phase 4 N=52 Ultrasound Guided Distal Peripheral Nerve Blocks and Postoperative Pain.
Postoperative Pain
Primary: Proportion of Patients Who Experienced Moderate to Severe Pain During First and Second Postoperative Day — 8.3; 80.8; 4.2; 42.3 percentage of patients
Phase 4 N=124 Effect of Intraoperative Anesthetic Management on Postoperative Nausea and Vomiting in Bariatric Surgery
Postoperative Nausea and Vomiting
Primary: PONV During the First 24 Hours After Bariatric Surgery — 22; 12 participants — p=0.04
Phase 4 N=26 Research Study for Major Depressive Disorder: Investigation of Glutamate Medications
Major Depression
Primary: Montgomery-Asberg Depression Rating Scale (MARDS) Score (Acute Response to IV Ketamine in Patients With Treatment Resistant Major Depression) — 24.4; 22.0 scores on a…