Phase 4 N=23 Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol
Prosthetic Joint Infection · Vancomycin · Joint Diseases
Primary: Systemic Vancomycin Level - Start of Case — 27.98; 0 ug/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=147 Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment
Obesity
Primary: Phase 1: Percent Weight Loss — 1.7; 0.9; 0.3 % change in weight
Phase 4 N=4,985 Alcohol Research Consortium in HIV-Intervention Research Arm
HIV Positive · Alcohol Use
Primary: Audit-C Score on a Scale — -1.0; -2.3; -1.0 score on a scale
Phase 4 N=202 Prospective Multicentre Phase-IV Clinical Trial of Olaparib in Indian Patients With Ovarian and Metastatic Breast Cancer
Ovarian Cancer · Breast Cancer
Primary: Haematology: Basophils Absolute Count, Eosinophils Absolute Count, Leucocytes WBC, Lymphocytes Absolute Count, Monocytes Absolute Count, Neutrophils Absolute Count, and…
Phase 4 N=57 Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response (NEMO)
Major Depressive Disorder
Primary: Change in Montgomery Asberg Depression Rating Scale Score — 18; 2; 3; 8 persons with positive treatment response
Phase 4 N=527 Zoster Eye Disease Study
Herpes Zoster Ophthalmicus
Primary: Number of Participants With the First Occurrence of New or Worsening Stromal Keratitis Without Ulceration (SK), Endothelial Keratitis (EK), Iritis (IR), Dendriform…
Phase 4 N=21 Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury
Hypotension, Orthostatic · Hypotension · Spinal Cord Injuries
Primary: Proportion of Systolic BP Within a Normotensive Range — 167; 117; 89 Systolic Blood Pressure Recordings
Phase 4 N=291 Evaluation of the Optimal MTX Dose as an Add-on Therapy to Adalimumab for RA Patients in Japan, South Korea and Taiwan
Rheumatoid Arthritis
Primary: Simple Disease Activity Index (SDAI) Remission Rate at Week 48 in mFAS — 25; 27 Participants
Phase 4 N=76 Minimizing Pain During Office Intradetrussor Botox Injection
Overactive Bladder · Overactive Detrusor · Overactive Bladder Syndrome
Primary: Pain: VAS — 25; 16 units on a scale, 0-100
Phase 4 N=96 Dosage of Epidural Morphine in Elderly Patients
Age Problem · Abdominal Cancer
Primary: Total Patient-controlled Analgesia (PCA) Morphine Sulphate (MS) Consumption. — 27.182; 9.182; 6.273; 38.136 mg
Phase 4 N=20 Vault Evaluation After ICL Implantation
Nearsightedness
Primary: Mean Difference Between Predicted and Actual Central Vault at 1-month After ICL Implantation — 0.170 Milimeters
Phase 4 N=124 Cool vs Room-temperature Artificial Tears
Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis) · Central Retinal Vein Occlusion With Macular Edema · Exudative Age-Related Macular Degeneration, Unspecified Eye
Primary: The Efficacy of Cooled Versus Room Temperature Artificial Tears in Reducing Post Intravitreal Injection Ocular Discomfort as Measured by Pain Scale Survey. — 2.21; 1.95…
Phase 4 N=50 A Study to Evaluate the Impact of Clascoterone 1% Cream on Skin Barrier Properties in Acne Prone Patients
Acne Vulgaris
Primary: The Primary Endpoint is the Change in Corneometry Reading Between the Two Sides of the Face Treated With Winlevi Versus no Treatment. — 131.27; 113.94 microSiemens (μS)…
Phase 4 N=167 Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral Fractures
Femur Fracture · Tibial Fractures
Primary: 12hrs VAS Pain Scores — 7.6; 7.9; 7.3; 7.2 score on a scale — p=0.215
Phase 4 N=477 A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression
Depressive Disorder, Treatment-Resistant
Primary: Double-blind Treatment Phase: Change in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score From Day 1 (Pre-randomization) to Day 28 — -7.0; -12.7; -13.9 Score…