Phase 4 N=175 Buspirone Treatment for Marijuana Dependence
Marijuana Dependence
Primary: Percent Marijuana-negative Urine Drug Screens (UDS) — 7.2; 6.4 percentage of UDS
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=303 Post Implantation/Post Market Evaluation of the Swedish Adjustable Gastric Band
Morbid Obesity
Primary: Re-operation Rate (Band Revision, Band Replacement and Explants Resulting From Serious Adverse Device-related Event {SADE}) of Gastric Banding at 4 and 5 Years Post…
Phase 4 N=383 A Follow-Up Study to WV19432, to Evaluate Long Term Post-Treatment Effects of PEGASYS (Peginterferon Alfa-2a(40KD))in Patients With HBeAg Positive Chronic Hepatitis B
Hepatitis B, Chronic
Primary: Percentage of Participants With Hepatitis B Envelope Antigen (HBeAg) Seroconversion. — 9.7; 14.6; 19.8; 31.6 Percentage of participants
Phase 4 N=44 Duration of Benefit for OnabotulinumtoxinA in Treatment of Chronic Migraine
Chronic Migraine
Primary: Subject Global Impression of Change — 4.43; 5.67; 1.67; 4.76 units on a scale
Phase 4 N=63 Efficacy of Single-Shot Dexmedetomidine Versus Placebo in Preventing Pediatric Emergence Delirium in Strabismus Surgery
Strabismus · Delirium on Emergence · Pediatric Disorders
Primary: Percentage of Patients Experiencing Pediatric Emergence Delirium in Strabismus Surgery — 50; 48 percentage of participants
Phase 4 N=97 Evaluation of an Absorbable Surgical Hemostatic Agent: Thrombi-Gel® Versus Gelfoam-Thrombin
Operation Site Bleed
Primary: The Primary Objective of This Investigation is to Gather Information to Support the Effectiveness of Thrombi-Gel as Compared to a Gelatin Sponge (Gelfoam) Plus Thrombin…
Phase 4 N=80 GenTeal in Perioperative Treatment of Laser Assisted in Situ Keratomileusis LASIK Patients
Corneal Epithelium Defect
Primary: Epithelial Healing After Laser Assisted in Situ Keratomileusis (LASIK) Surgery — 4.3; 3.5; 9.2; 9.0 Clock Hours
Phase 4 N=30 Body Temperature in Persons With Tetraplegia When Exposed to Cold
Tetraplegia · Hypothermia · Mild Cognitive Impairment
Primary: Visit 1: Percent Change in Core Body Temperature — -1.2; 0.05 Percent Change — p=<0.01
Phase 4 N=23 Small Bowel Capsule Endoscopy Findings in Patients Receiving Cellcept®
Gastrointestinal Lesions · Signs and Symptoms, Digestive
Primary: GI Mucosal Lesions Change and Clinical Symptoms Using The Gastrointestinal Symptom Rating Scale (GSRS) Score — 2.99; 2.19 GSRS score — p=0.05
Phase 4 N=48 A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Copegus (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Enrolled in a Methadone Maintenance Treatment Program.
Hepatitis C, Chronic
Primary: Number of Participants With Treatment Completion Rate (TCR) — 9; 10; 4; 5 participants
Phase 4 N=93 The SIM-SOF Trial for Hepatitis C
Chronic Hepatitis C
Primary: Proportion of Participants With Sustained Virologic Response 12 (SVR-12) — 54; 18 participants — p=.02
Phase 4 N=74 Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Acute Myocardial Infarction
ST-segment Elevation Myocardial Infarction · Non-ST-segment Elevation Myocardial Infarction · VA Drug Interactions
Primary: Area Under the Plasma Concentration-time Curve for Ticagrelor (AUC 0-12h) — 6307; 9791 ng*h/mL
Phase 4 N=171 Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomy
Otitis Media
Primary: Maximum Postoperative Face, Legs, Activity, Cry and Consolability (FLACC) Pain Score. — 2.9; 2.7; 2.0 units on a scale — p=0.21
Phase 4 N=68 Melatonin in Smoke-induced Vascular Injury
Smoking · Vascular System Injuries
Primary: Smoke-induced Vascular Injury and Melatonin's Effect in This Process Assessed by the Concentration of Fbg. — 2.76; 2.38; 2.89; 2.49 g/L
Phase 4 N=33 Alpha Lipoic Acid for Treatment of Diabetic Neuropathy
Diabetic Neuropathy
Primary: Total Symptoms Score — 2.5; 3.1 units on a scale — p=< 0.05