Phase 4 N=96 Postpartum Etonogestrel Implant for Adolescents
Adolescence · Contraception · Postpartum
Primary: Continuation at 1 Year — 21; 30 participants
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=6,075 Health Information Technology (HIT) Enhanced Family History Documentation and Management in Primary Care
Colorectal Cancer · Breast Cancer · Coronary Heart Disease
Primary: Number of Subjects Who Discussed Disease Risk With Primary Care Provider — 905; 841 Participants
N/A N=54 Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
Insomnia · Depression · Posttraumatic Stress Disorder
Primary: Columbia Suicide Severity Rating Scale (C-SSRS) — 5.4; 8.4 units on a scale — p=.153
Phase 2 N=14 Acamprosate in Youth With Fragile X Syndrome
Fragile X Syndrome · Autism Spectrum Disorders
Primary: Clinical Global Impression- Severity Scale (CGI-S) — 7.0 units on a scale
Phase 3 N=218 Topical DHEA Against Vaginal Atrophy
Vaginal Atrophy
Primary: Co-primary Endpoint: Change From Baseline to Week 12 of Vaginal Cell Maturation (Percentage of Parabasal Cells) — 46.7; 65.5; 53.4; 61.8 percentage of parabasal cells
Phase 2 N=31 Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine Dependence
Cocaine Dependence
Primary: Functional MRI Activation Patterns in the Nucleus Accumbens and Amygdala in Response to Cocaine Cues
Phase 2 N=152 Ranibizumab for Edema of the Macula in Diabetes: Protocol 3 With High Dose - the READ 3 Study
Diabetic Macular Edema
Primary: Deaths Due to Myocardial Infarction — 1; 3 participants
Phase 4 N=30 Benzocaine Versus Placebo Spray for Pain Relief at Hysterosalpingogram
Pain Relief · Analgesia
Primary: Change in Pain Score — 50.6; 70.4 mm — p=0.43
Phase 3 N=369 Immunogenicity and Safety Study of GSK Biologicals' Meningococcal Vaccine Given as One Dose to Healthy Subjects Above 56 Years
Infections, Meningococcal
Primary: Vaccine Response to Meningococcal Antigens (MenA, MenC, MenW-135 and MenY) — 134; 55; 151; 56 Participants
N/A N=8 Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies
Low Back Pain
Primary: Percentage of Patients With Magnetic Resonance Imaging (MRI) Evidence of Tissue Ablation/Edema at Targeted Lumbar Medial Branches — 100 percentage of participants
Phase 2 N=38 Continuous Administration of Oral Contraceptive, Primary Dysmenorrhea
Dysmenorrhea
Primary: Change in Visual Analog Scale (VAS) Score — -74.8; -58.7 units on a scale — p=0.05
N/A N=9 Enema Use and Acceptability in HIV Negative Men Who Have Sex With Men
HIV Infections
Primary: Mucosal Toxicity Using Histopathology — 0.6; 0.5; 4.2 units on a scale — p=<.05
Phase 3 N=126 Does Fish Oil Prevent Depression in Pregnancy and Postpartum?
Depression
Primary: Beck Depression Inventory — 7.9; 6.5; 6.3; 7.4 units on a scale — p=.29
Phase 1 N=31 Yervoy With Sylatron Unresectable Stage 3 or 4 Melanoma
Melanoma
Primary: Maximum Tolerated Dose (MTD) of Sylatron — 2 μg/kg s
N/A N=96 The EASYTRAK EPI Clinical Investigation
Bradycardia · Congestive Heart Failure
Primary: Chronic Pacing Thresholds at 3 Months — 0.9 V