12,372 trials
Heart Failure
Primary: Occurrence of the Composite Endpoint of Cardiovascular Death and Total (First and Recurrent) Heart Failure Events — 1083; 1283 events — p=0.0072
Pregnancy Related · Anemia, Iron Deficiency
Primary: Median Change in Hemoglobin Value Before and After Intervention — 10.95; 11.45 g/dL — p=< 0.001
Lymphoma
Primary: 3 Years Event-free Survival — 51; 56; 126; 123 Participants
Diabetes Mellitus, Type 2
Primary: Change in Glycated Haemoglobin (HbA1c) — -1.68; -1.31 Percentage of HbA1c — p=<0.0001
Lung Neoplasms · Non-Small-Cell Lung Carcinoma
Primary: Overall Survival (OS) in Participants With PD-L1 TPS ≥50% — 15.7; 20.3 Months — p=0.6712
Irritability Associated With Autism Spectrum Disorder
Primary: Change From Baseline at Week 6 in Caregiver-rated Aberrant Behavior Checklist Irritability (ABC-I) Subscale Score — -9.6; -11.2; -11.2 score on a scale — p=0.2986
Pulmonary Arterial Hypertension
Primary: Time to First Confirmed Morbidity or Mortality Event — NA; 9.6 Months
Ventricular Tachycardia · Atrial Fibrillation
Primary: Amount of Treated Subjects With Freedom of Symptomatic Post-procedural AF or Flutter at 12 and 15 Months Post Procedure and Less Than 1 Min/Day of AF or Flutter on…
Acute Coronary Syndrome
Primary: Percent Change From Baseline to Day 330 in LDL-C — -45.6; 1.4 Percent change in LDL-C — p=< 0.001
Chronic Spontaneous Urticaria
Primary: Change From Baseline in Weekly Itch Severity Score at Week 24 — -6.01; -10.24; -4.81; -7.68 score on a scale — p=0.0005
Acute Myeloid Leukemia (AML)
Primary: Number of Participants With Dose-Limiting Toxicities (DLTs) of Venetoclax in Combination With Azacitidine (AZA) (Part 1) — 3; 4; 4; 1 Participants
Obesity · Heart Failure With Preserved Ejection Fraction (HFpEF)
Primary: Change From Baseline in the Kansas City Cardiomyopathy Questionnaire (KCCQ) Clinical Summary Score (CSS) — 19.51; 12.68 Score on a scale — p=<0.001
Anatomic Stage 0 Breast Cancer AJCC v8 · Anatomic Stage I Breast Cancer AJCC v8 · Anatomic Stage IA Breast Cancer AJCC v8
Primary: Proportion of Patients With Grade 2 or Greater Reactions That Require Parenteral Rescue Medications to Treat an Infusion Hypersensitivity Reaction (HSR) After the First…
Postmenopausal Women With Osteoporosis
Primary: Percentage Change in Lumbar Spine BMD (Bone Mineral Density) — 1.698; 1.440 Percent change
Cardiac Surgery Intensive Care Treatment · Delayed Recovery From Anaesthesia · Euthyroid Sick Syndrome
Primary: Change in Glasgow Coma Scale (GCS) From Intervention Initiation to ICU Discharge (Δ) — 6.65; 2.69 Score on a scale